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Chemistry Nobel goes to Jacques Dubochet, Joachim Frank, and Richard Henderson. 

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image: Nonviral CRISPR Delivery a Success

Nonviral CRISPR Delivery a Success

By | October 2, 2017

Researchers use gold nanoparticles to deliver CRISPR-Cas9 and correct a point mutation in a mouse model of Duchenne muscular dystrophy. 

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image: Metabolomics Data Under Scrutiny

Metabolomics Data Under Scrutiny

By | September 15, 2017

Out of 25,000 features originally detected by metabolic profiling of E. coli, fewer than 1,000 represent unique metabolites, a study finds.

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image: Robotic Patch Clamping Gains Eyes

Robotic Patch Clamping Gains Eyes

By | August 30, 2017

Two groups of scientists combined automation with two-photon microscopy to target and record specific neurons in living animals. 

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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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image: Do Preprints Require More Rigorous Screening?

Do Preprints Require More Rigorous Screening?

By | August 1, 2017

Two manuscripts published without methods point to the importance of community policing on preprint archives.

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image: Zebrafish Embryos Survive Deep Freeze and Quick Thaw

Zebrafish Embryos Survive Deep Freeze and Quick Thaw

By | July 28, 2017

In a first, scientists reanimate the fish using embedded gold nanoparticles that heat up cells by absorbing laser light.

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A new method stimulates B cells to make human antigen-specific antibodies, obviating the need for vaccinating blood donors or hunting for rare B cells.

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image: Image of the Day: A Swell Idea

Image of the Day: A Swell Idea

By | July 19, 2017

To improve the resolution of biological samples at the cellular level, researchers inflate tissues with “swellable polymers” so that they’re easier to see under the microscope.    

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image: Mini-Metagenomics Leads to Microbial Discovery

Mini-Metagenomics Leads to Microbial Discovery

By | July 14, 2017

Researchers develop a method that combines the strengths of shotgun metagenomics and single-cell genome sequencing in a microfluidics-based platform.

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