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tag cytochrome p450 genetics genomics

Allele Shows Pyrethroid Resistance’s Spread in African Mosquitos
Carolyn Wilke | Mar 22, 2019 | 4 min read
Researchers can now track the expansion of a resistance mechanism that allows the malaria vector Anopholes funestus to detoxify a key insecticide used on bed nets.
Forging Ahead on Arabidopsis
Barry Palevitz | Oct 28, 2001 | 4 min read
With completion of the genome sequence of the tiny mustard plant Arabidopsis imminent, researchers began anticipating the logical next step. Meeting in the fall of 1998 and again in January 2000 under the aegis of the National Science Foundation, they drew up a plan called the 2010 Project, which, if successful, would catalog the functions of all of 'the weed's' 25,000 or so genes. Their goal was ambitious: "to understand every molecular interaction in every cell throughout a plant life cycle."1
2018 Top 10 Innovations
The Scientist | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.
New Technologies Shed Light on Caveolae
Ben Nichols | Jun 1, 2018 | 10+ min read
The functions of the cellular invaginations identified more than half a century ago are now beginning to be understood in detail.
Medicine Gets Personal
Jeffrey Perkel(jperkel@the-scientist.com) | Apr 24, 2005 | 9 min read
Given accelerated approval in 1996, the chemotherapy drug irinotecan (Camptosar) can attack metastatic colorectal cancers that don't respond to other drugs.
Top 10 Innovations 2016
The Scientist | Dec 1, 2016 | 10+ min read
This year’s list of winners celebrates both large leaps and small (but important) steps in life science technology.
RNA Interference Between Kingdoms
Kerry Grens | Feb 1, 2017 | 10+ min read
Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of pesticides.
Rosy Outlook for Blue Roses
Michael Szpir | Jun 19, 2005 | 3 min read
More than $27 billion worth of cut flowers are sold in the global marketplace every year.
Reducing Malaria to its Constituent Parts
Eugene Russo | May 23, 2004 | 5 min read
FIRST BITE:Courtesy of CDC/Jim GathanyFemale Anopheles gambiae mosquito feeding.A decade ago, scientists around the world recognized that despite malaria's tremendous disease burden, research on the topic had stagnated. With funding at low levels, robust molecular biology tools numbered few. Today, genome sequences for Plasmodium falciparum, the parasite causing malaria, and for Anopheles gambiae, the mosquito that spreads it, have already fundamentally changed the research landscape. Plasmodium

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