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tag mitochondrial disease neuroscience disease medicine

Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
First fix for mitochondrial diseases
Victoria Stern | Aug 25, 2009 | 2 min read
Researchers replace defective mitochondrial genomes with healthy ones in monkey embryos—a technique that could be used to prevent children from inheriting a variety of incurable genetic diseases caused by defective mitochondrial genes.
A false color transmission electron microscope micrograph showing the nuclear envelope, the rough endoplasmic reticulum, the nucleus, and the cytoplasm.
New Gene Mutants Identified in Rare Motor Neuron Diseases
Clare Watson | Oct 17, 2022 | 2 min read
The discovery of gene variants in cases of hereditary spastic dysplasia could provide a diagnosis to affected families where no genetic cause could be found before.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
The Genes of Parkinsonā€™s Disease
Bobby Thomas and M. Flint Beal | Feb 1, 2011 | 10 min read
The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Microscopy image of a fluorescent green oligodendrocyte surrounded by astrocytes stained red with blue nuclei.
Searching for a Direct Route to Multiple Sclerosis Treatment
Deanna MacNeil, PhD | Jul 17, 2023 | 3 min read
Researchers created a new high-throughput tool to hunt for therapies that remyelinate the nervous system.
Neuro collage
Our Favorite Neuroscience Stories of 2021
Chloe Tenn | Dec 29, 2021 | 4 min read
From a Nobel prize and photosynthesis-powered brains to neurodegeneration research and controversy over a new Alzheimer’s drug, a look back at some of the biggest brain-related developments of the year.
defect in Huntington's disease
Tudor Toma(t.toma@ic.ac.uk) | Jul 1, 2002 | 1 min read
In Huntington's disease mutant huntingtin protein has a direct effect on mitochondria, causing calcium handling defects.
Amyloid plaques on axons of neurons
The Misunderstood Proteins of Neurodegeneration
Catherine Offord | Aug 1, 2022 | 10+ min read
The normal functions of peptides that aggregate in Alzheimer’s, Parkinson’s, and Huntington’s have been largely overlooked by scientists, but some argue that they are critical for understanding the development of disease.

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