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tag dna double stranded breaks evolution developmental biology

A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Illustration of DNA
Can “Gene Writing” Deliver What Gene Editing Can’t?
Dan Robitzski | Dec 12, 2022 | 10+ min read
A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?
Genetics Models Move Beyond Drosophila and the Humble Lab Mouse
Amber Dance | Sep 1, 2019 | 8 min read
Organisms with unusual genomes are helping scientists investigate gene regulation, evolution, and development.
Sticky fingers
Ionel Sandovici and Carmen Sapienza | Jun 1, 2010 | 4 min read
By Ionel Sandovici and Carmen Sapienza Sticky fingers A single protein recognizes different sequences in different organisms and drives speciation. Computer graphic of a two zinc-finger peptide (yellow) binding to a DNA (red and blue) molecule. © KEN EWARD / BIOGRAFX / SCIENCE PHOTO LIBRARY Homologous recombination physically links together chromosomes at the first division in meiosis by sharing DNA strands between chromosomes. This creates genetic variat
Green-tinged image of fly eye with shiny and black portions
New CRISPR Technique Causes Few Unintended Mutations in Fruit Flies
Jason P. Dinh | Jul 1, 2022 | 4 min read
A study finds that CRISPR-Nickase, which changes just one allele of a given gene, improves gene editing efficiency compared with CRISPR-Cas9.
Heliconius erato demophoon butterfly mullerian mimicry wnta
Gene Regulation Gives Butterflies Their Stunning Looks
Katarina Zimmer | Nov 14, 2019 | 5 min read
Distantly related, lookalike Heliconius species arrive at the same appearance using the same few genes, but regulated differently, according to recent studies.
CRISPR, Cas-9, Nobel, Chemistry
CRISPR’s Adaptation to Genome Editing Earns Chemistry Nobel
Amanda Heidt | Oct 7, 2020 | 4 min read
Emmanuelle Charpentier and Jennifer Doudna reprogrammed the bacterial immune response into one of the most popular tools for genetics and molecular biology.
Bacteria and Humans Have Been Swapping DNA for Millennia
Kelly Robinson and Julie Dunning Hotopp | Oct 1, 2016 | 8 min read
Bacteria inhabit most tissues in the human body, and genes from some of these microbes have made their way to the human genome. Could this genetic transfer contribute to diseases such as cancer?
labtools march 2019 the scientist dna
The Challenge of Using CRISPR to Knock In Genes
Anna Nowogrodzki | Mar 1, 2019 | 7 min read
Researchers are developing an array of techniques for accurately and efficiently inserting genes into DNA.

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