ADVERTISEMENT
Infographic showing how neurodegenerative diseases have long been associated with aggregations of apparently toxic proteins
Infographic: Secret Lives of Neurodegeneration-Linked Proteins
Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain.
Infographic: Secret Lives of Neurodegeneration-Linked Proteins
Infographic: Secret Lives of Neurodegeneration-Linked Proteins

Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain.

Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain.

Alzheimer's Disease, disease & medicine

Updated
blue and white sign for the entrance to the FDA that says U.S. Department of Health and Human Services Food and Drug Administration
Biogen’s Alzheimer’s Drug Gets FDA Approval, Mixed Reviews
Kerry Grens | Jun 7, 2021 | 2 min read
A lackluster performance in clinical trials of the monoclonal antibody aducanumab has left some experts unconvinced of its benefit.
A microscopy image of a mouse brain that shows the lymphatic system in bright purple and pink
Brain’s Lymphatic System Tied to Alzheimer’s Symptoms in Mice
Amanda Heidt | May 4, 2021 | 5 min read
A dysfunctional lymphatic system, described as a clogging of the brain’s sink, may explain why immunotherapies fail in some Alzheimer’s patients.
Breaking Down Barriers
The Scientist | 1 min read
Looking at the future of neurodegeneration research!
Eli Lilly Claims New Drug Can Slow Alzheimer’s-Related Decline
Lisa Winter | Mar 16, 2021 | 2 min read
Patients who received the drug fared better cognitively and functionally than those taking placebo, but still experienced losses in performance.
Reduced Adult Neurogenesis Linked with Alzheimer’s Disease
Abby Olena, PhD | Feb 1, 2021 | 6 min read
Manipulating the production of new neurons can improve cognition in animal models of the disease, raising the possibility that figuring out a way for humans to make more neurons could make a difference for people with dementia.
bace1 alzheimer's disease gga3 axon neuron
Alzheimer’s-Linked Mutation Causes Blockages in Neurons
Ian Le Guillou | Nov 20, 2020 | 3 min read
The variant causes a buildup of BACE1 protein in axons in cultured neurons and mice. Researchers say it might be time to rethink failed trials that inhibit BACE1 to treat the neurodegenerative disease.
a patient getting blood drawn for testing
First Alzheimer’s Blood Test Rolled Out for Clinical Use in US
Shawna Williams | Nov 2, 2020 | 4 min read
The test will be a cheaper and more accessible alternative to currently available diagnostic tools, researchers say.
tau p-tau217 amyloid amyloid-beta alzheimer's disease blood test
Experimental Blood Test Could Flag Alzheimer’s
Kerry Grens | Jul 29, 2020 | 2 min read
New studies show that elevated levels of a form of tau called p-tau217 can accurately distinguish Alzheimer’s disease from other forms of dementia, and perhaps even predict it.
Alzheimer's Disease, Neurology, Influenza, Pneumonia, Vaccine, Pneumococcal, Immune System, Dementia
Flu and Pneumonia Vaccines Linked to Reduced Risk of Alzheimer’s
Amanda Heidt | Jul 27, 2020 | 3 min read
The authors propose that the shots might keep the immune system primed to battle diseases that would otherwise contribute to cognitive decline.
Early Detection of Dementia with Smart Devices
Rachael Moeller Gorman | May 1, 2020 | 10+ min read
Digital biomarkers of cognitive decline could alert us to the early stages of dementia before irreversible damage occurs.
Neuroscientist Phil Haydon Sets Sail to Talk About Epilepsy
Ashley Yeager | Feb 19, 2020 | 6 min read
After an accident as a teenager, he developed the disorder. He then studied the brain to better understand his own seizures, and now plans to sail around the world to show others with the condition how to push their limits.
herpes virus hhv6 hhv6a hhv6b alzheimer's disease
Study Finds No Association Between Herpes Virus and Alzheimer’s
Katarina Zimmer | Jan 23, 2020 | 5 min read
While the findings contradict previous studies that have linked human herpesvirus 6 to the neurodegenerative disease, they do not eliminate the possibility of a relationship.
Interactive: Biomarkers in Blood Provide a Window into the Brain
Shawna Williams | Dec 1, 2019 | 1 min read
A look at some of the circulating molecules that may indicate various Alzheimer’s pathologies and serve as the bases of noninvasive tests for the disease.
The Hunt for a Blood Test for Alzheimer’s Disease
Shawna Williams | Dec 1, 2019 | 10 min read
Researchers hope circulating biomarkers will enable earlier detection and better monitoring of the neurodegenerative disorder—and perhaps help usher in new treatments.
Scientists Criticize Mouse Study of New Alzheimer’s Drug
Emily Makowski | Nov 13, 2019 | 3 min read
Oligomannate, recently approved in China, is being met with some skepticism from researchers.
oligomannate alzheimer's disease neurodegeneration microbiome seaweed drug approval china
China Approves Alzheimer’s Treatment that Targets the Microbiome
Kerry Grens | Nov 5, 2019 | 2 min read
Oligomannate, derived from a compound in seaweed, suppresses neural inflammation caused by gut bacteria in mice.
Air Pollution May Damage People’s Brains
Catherine Offord | Oct 1, 2019 | 10+ min read
Contaminants in the atmosphere appear to have harmful effects on neurodevelopment and cognitive function.
Genetic Risk for Alzheimer’s Disease Linked to Highly Active Brains
Diana Kwon | Oct 1, 2019 | 5 min read
A growing body of evidence supports the theory that neural hyperactivity and hyperconnectivity precede the pathological changes that lead to neurodegeneration.
Tau Pathology Present Decades After a Single Brain Injury
Ruth Williams | Sep 9, 2019 | 3 min read
Patients who suffer a traumatic brain injury may exhibit abnormally abundant tau protein many years later, a new in vivo imaging technique reveals.
ADVERTISEMENT