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tag short bowel syndrome genetics genomics ecology immunology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
3D illustration of a tapeworm infestation in a human intestine
Return of the Worms
Catherine Offord | Dec 1, 2021 | 10+ min read
Immunologists and parasitologists are working to revive the idea that helminths, and more specifically the molecules they secrete, could help treat allergies and autoimmune disease.
Natural Killer Cell Therapies Catch Up to CAR T
Bianca Nogrady | Apr 1, 2020 | 8 min read
There’s a new cell-based cancer immunotherapy on the block.
How Well Do Mice Model Humans?
Ricki Lewis | Oct 25, 1998 | 8 min read
STRIKING RESEMBLANCE: James Croom, who studies Down syndrome mice at North Carolina State University, says the animals are providing valuable information useful to humans. When a page-one article in the May 3, 1998, Sunday New York Times portrayed angiogenesis inhibitors that fight cancer in mice as being possible just around the corner for humans, criticism for raising false hopes erupted. Merely 10 weeks later, however, when researchers from the University of Hawaii reported cloning the fi
Lurking in the Shadows
Bob Grant | Dec 1, 2014 | 10+ min read
Bats harbor diverse pathogens, including Ebola, Marburg, SARS, and MERS viruses. Understanding why could help researchers stymie deadly emerging diseases.
Vaccines: Victims of Their Own Success?
Ricki Lewis | Jul 18, 2004 | 10+ min read
Perhaps in no area is the divide between the developed and developing worlds as striking as it is for vaccines: While healthcare consumers in economically advantaged nations worry about risk, in developing nations compelling need forces a focus on potential benefit. "People in the United States want a quick solution, not prevention, so they prefer drugs to vaccines. Elsewhere, people are afraid of drugs and side effects, and prefer vaccines," says Shan Lu, a primary-care physician who has worked
New Molecular Targets Reviving Anti-Inflammatory Therapeutics
Karen Young Kreeger | Jul 6, 1997 | 7 min read
Photo: Roger Riley NEW UNDERSTANDING: Kelvin Cooper predicts an upswing in interest because of new developments like comprehending the cytokine signaling pathway. Biochemical message-routing molecules are being discovered regularly, giving researchers new targets for developing more efficacious therapeutics to treat inflammatory disease. According to industry observers, these therapies constitute a multibillion-dollar market for treating disorders such as asthma, lupus, multiple sclerosis, ost

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