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tag physics disease medicine ecology genetics genomics microbiology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
In Defense of Ecology
Jonathan Shurin | Jan 21, 2001 | 3 min read
Raymond J. O'Connor1 attributes what he calls the "faltering progress of ecological research" to lack of creativity on the part of ecologists and a failure to follow the examples of more "successful" sciences (e.g., molecular genetics and physics). We agree that ecology would benefit from a greater emphasis on generality and conceptual unification. However, we take issue with both the contention that ecological science has failed to progress and that the approaches of other disciplines can be ap
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
The Ecology of Tumors
Paraic A. Kenny, Celeste M. Nelson, and Mina J. Bissell | Apr 1, 2006 | 10+ min read
FEATUREThe Ecology of Tumors   Courtesy of Nasa Ames Research CenterBy perturbing the microenvironment, wounds and infection may be key to tumor development.BY PARAIC A. KENNY, CELESTE M. NELSON, AND MINA J. BISSELLNo tumor is an island. Chemical and physical forces exerted by the diverse cellular populations that surround a tumor - its so-called microenvironment - shape development and progression. Manipulating these 'ecologi
The cholera genome: an advance for science or for medicine?
Robert Walgate | Aug 7, 2000 | 6 min read
genome sequence will help in developing protection against the disease. Robert Walgate discovers that it might - but perhaps not in the most obvious ways.
A fruit bat in the hands of a researcher
How an Early Warning Radar Could Prevent Future Pandemics
Amos Zeeberg, Undark | Feb 27, 2023 | 8 min read
Metagenomic sequencing can help detect unknown pathogens, but its widespread use faces challenges.
Bacteria and Humans Have Been Swapping DNA for Millennia
Kelly Robinson and Julie Dunning Hotopp | Oct 1, 2016 | 8 min read
Bacteria inhabit most tissues in the human body, and genes from some of these microbes have made their way to the human genome. Could this genetic transfer contribute to diseases such as cancer?
Researchers Catalog Earth’s Microbiome
Katarina Zimmer | Feb 1, 2018 | 5 min read
The new database includes data from 27,000 samples collected at sites ranging from Alaskan permafrost to the ocean floor.

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