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tag synaptic homeostasis cell molecular biology

A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Synaptic Vesicles: Reused or Recycled?
Jill Adams | Oct 24, 2004 | 8 min read
VISUALIZING VESICLES:© 2003 Nature Publishing GroupIn A, researchers used a fluorescent protein (synaptopHluorin) to visualize synaptic vesicle movement. Some vesicles stay open briefly before retrieval (kiss-and-run). Others stay open longer but also don't collapse fully into the plasma membrane (compensatory). Still others collapse and are not retrieved until another stimulus is delivered (stranded). In B, another group used a dye FM1-43, to study vesicle retrieval and found that single v
A Weighty Matter: Neuropeptides Involved In Appetite And Energy Homeostasis
Deborah Wilkinson | Sep 12, 1999 | 10+ min read
Date: September 13, 1999Table of Neurochemical Manufacturers The hypothalamus has long been known as a control center for feeding and weight control behaviors. Complex regulatory feedback loops enable this portion of the brain to determine satiety and metabolic activity. Not surprisingly, the control mechanisms are complex and involve different biochemical pathways.1,2,3 Image courtesy of Jeffrey M. Friedman An ob/ob mouse stacking up against its lean counterparts A series of pioneering expe
Vlad Denic on Exploring New Fields and Failing Successfully
Ben Andrew Henry | Dec 1, 2016 | 3 min read
The Harvard professor is pursuing fundamental questions about autophagy, protein homeostasis, and other cellular processes, and he’s always on the lookout for his next new topic.
Complete model of fly brain neuron connections
How Larval Fruit Fly Brains Convert Sensory Signals to Movement
Laura Dattaro, Spectrum | Mar 10, 2023 | 4 min read
A wiring map diagrams more than half a million neuronal connections in the first complete connectome of Drosophila and holds clues about which brain architectures best support learning.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
The Scientist Staff | Mar 28, 2024
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
T Cells and Neurons Talk to Each Other
Ashley Yeager | Oct 1, 2020 | 10+ min read
Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.

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