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bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Updated Sept 1
coronavirus pandemic news articles covid-19 sars-cov-2 virology research science
Follow the Coronavirus Outbreak
The Scientist | Feb 20, 2020 | 10+ min read
Saliva tests screen staff and students at University of Illinois; Study ranks species most susceptible to SARS-CoV-2 infection; COVID-19 clinical trials test drugs that inhibit kinin system
Gut harbors antibiotic resistance
Bob Grant | Aug 26, 2009 | 3 min read
The millions of microbes that crowd the human intestinal tract are teeming with new antibiotic resistance genes that could jump to disease-causing pathogens, according to researchers from Harvard University.An artist's conception of microbialecology in the gut. Pathogenic bacteria(green coats) receiving Penicillinresistance genes from beneficialgut bacteria (blue rounded chains)Image courtesy of A. Canossa, M.Sommer and G. Dantas They found more than 90 undiscovered bacterial genes capable of c
African Sleeping Sickness: A Recurring Epidemic
Ricki Lewis | May 12, 2002 | 5 min read
African trypanosomiasis is making an unwelcome comeback. But unlike other returning diseases, this one has a drug treatment—eflornithine—that disappeared from the market when it failed to cure cancer. Yet like Viagra's origin from a curious side effect in a clinical trial, so too was eflornithine reborn. "When it was discovered that it removes mustaches in women, it suddenly had a market: western women with mustaches," says Morten Rostrup, president of the international council for M
Notebook
The Scientist Staff | Oct 25, 1998 | 7 min read
BIOREMEDIATION TO THE PIGPEN It was a stinky summer at the EnviroPork hog facility near Larimore, N.D., with penalties pending for violating state odor regulations, and neighbors complaining loudly about the foul fragrance. Making matters worse, the manure lagoon associated with the facility threatened groundwater supplies. Happily, researchers from the University of North Dakota Energy and Environmental Research Center (EERC) had a low-tech solution: barley straw. Using a cannon, they shot a
Mafia Wars
Jef Akst | May 31, 2010 | 10+ min read
An increasing amount of data is showing that the cellular battle between pathogens and hosts needs much more than a simple military metaphor to describe it—think undercover infiltration, front organizations, and forced suicide.
60 Members Elected to NAS
Barry Palevitz | Jun 25, 2000 | 6 min read
Editor's Note: On May 2, the National Academy of Sciences announced the election of 60 new members and 15 foreign associates from nine countries in recognition of their distinguished and continuing achievements in original research. Nearly half of the new members are life scientists. In this article, The Scientist presents photographs of some of the new members and comments from a few of them on their careers and on past and current research. A full directory of NAS members can be found online a
Articles Alert
Bernard Dixon | Mar 5, 1989 | 7 min read
LIFE SCIENCES BY BERNARD DIXON European Editorial Offices The Scientist Uxbrldge, U.K. " Positron emission tomography studies in 20 Swedish army officer cadets have revealed metabolic changes in the same regions of the brain during both tactile learning and tactile recognition. This exciting glimpse of brain metabolism accompanying conscious activity appears in a new journal launched by the European Neurosciences Association and designed to interest the entire universe of neuroscientists, fro
Jumping Genes A Buyers' Guide
Hillary Sussman | Jun 15, 2003 | 6 min read
Courtesy of Ivan Rayment  CAUGHT IN MID HOP: Structure of the Tn5 transposase/DNA complex No one believed Barbara McClintock in 1951 when she first described DNA that "jumped" from site to site within maize chromosomes, altering the expression of genes near the sites of integration. In due course, these transposable elements, or transposons, were found to be ubiquitous in nature, and 30 years later McClintock won the Nobel Prize. Today transposons have gone from molecular oddity to molec

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