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image: Vlad Denic on Exploring New Fields and Failing Successfully

Vlad Denic on Exploring New Fields and Failing Successfully

By | December 1, 2016

The Harvard professor is pursuing fundamental questions about autophagy, protein homeostasis, and other cellular processes, and he’s always on the lookout for his next new topic.

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image: Autophagy Pioneer Wins Nobel

Autophagy Pioneer Wins Nobel

By | October 3, 2016

Biologist Yoshinori Ohsumi is honored for his discoveries on the mechanisms of cellular recycling.

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image: Cocaine Induces Neuronal Autophagy

Cocaine Induces Neuronal Autophagy

By | January 19, 2016

A new study supports the idea that cocaine triggers brain cells to eat themselves and suggests a possible antidote.

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image: Targeted ER Breakdown

Targeted ER Breakdown

By | June 17, 2015

Researchers identify receptors that target the endoplasmic reticulum for degradation by autophagy in yeast and mice. 

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Synaptic Pruning Improves Autism in Mice

Synaptic Pruning Improves Autism in Mice

By | August 25, 2014

Fixing impaired pruning and autophagy signaling in neurons eases the symptoms of autism in a mouse model of the disorder.

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image: Autophagy Revives Dying Cancer Cells

Autophagy Revives Dying Cancer Cells

By | April 7, 2014

Self digestion thwarts self destruction.  

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image: Waste-Management Consultant

Waste-Management Consultant

By | November 1, 2013

By audaciously pursuing an abandoned area of research, Ana María Cuervo discovered how cells selectively break down their waste, and revealed the health consequences when that process malfunctions.

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image: Autophagy’s Role in Alzheimer’s

Autophagy’s Role in Alzheimer’s

By | October 3, 2013

Researchers show that amyloid beta is secreted from neurons in an autophagy-dependent manner.

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image: Citations Predict Nobel Winners?

Citations Predict Nobel Winners?

By | September 25, 2013

Thomson Reuters makes its annual data-based picks for which scientists could collect medals in Stockholm later this year.

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