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tag autoimmune disease cell molecular biology culture

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
Decoding the Cellular Secrets of the Endometrium 
Deanna MacNeil, PhD | Jan 16, 2024 | 3 min read
Endometrial organoids and single cell analyses helped uncover the molecular mechanisms of a rare uterine condition.
3D illustration of damaged myelin sheath seen in demyelinating diseases such as multiple sclerosis.
Tracking Down Innate Immune Cells in Multiple Sclerosis
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 5 min read
A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.
Molecular Biology
The Scientist Staff | Dec 6, 1992 | 2 min read
R. Glynne, S. H. Powis, S. Beck, A. Kelly, L-A. Kerr, J. Trowsdale, "A proteasome-related gene between the two ABC transporter loci in the class II region of the human MHC," Nature, 353:357-360, 1991. Richard Glynne (Imperial Cancer Research Fund, London, England): "The mechanism by which the body's immune system recognizes and kills virally infected cells but passes over healthy cells has intrigued immunologists for many years. An important breakthrough came when Alain Townsend at the John R
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
A twisted and folded illustration of single-stranded RNA in front of a blue background.
Deficient RNA Editing Implicated in Inflammatory Disease 
Alejandra Manjarrez, PhD | Aug 5, 2022 | 3 min read
Genetic variants that reduce the editing levels of double-stranded RNA are associated with autoimmune and immune-mediated conditions, a study finds.
Top 7 cell biology papers
Jef Akst | Jul 12, 2010 | 3 min read
#1 Gene for autoimmunity Rare genetic variants in the protein sialic acid acetylesterase (SASE) are linked to common human autoimmune diseases, including type 1 diabetes, arthritis, and Crohn's disease. In mice, defects in the protein have been linked to problems in B-cell signaling and the development of auto-antibodies. I. Surolia, et al., "Functionally defective germline variants of sialic acid acetylesterase in autoimmunity," Nature, 466:243-7. Epub 2010 Jun 16. linkurl:Eval;http://f1000b

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