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image: Biochemistry Pioneer Dies

Biochemistry Pioneer Dies

By | June 3, 2015

Irwin “Ernie” Rose, who shared the 2004 Nobel Prize in Chemistry for his work on ubiquitin-mediated protein degradation, has passed away at age 88.


image: Cellular Garbage Disposal Illuminated

Cellular Garbage Disposal Illuminated

By | April 13, 2015

A Harvard team shows how cells label and recognize proteins for degradation.


image: Neil Bence: Manipulating Degradation

Neil Bence: Manipulating Degradation

By | December 1, 2012

Senior Scientist, Millennium Pharmaceuticals: The Takeda Oncology Company Age: 39


image: Ubiquitin Chains in Action

Ubiquitin Chains in Action

By | July 1, 2012

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role


image: Daniel Durocher: Change is Good

Daniel Durocher: Change is Good

By | July 1, 2012

Senior Investigator, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada. Age 40


image: On the Chain Gang

On the Chain Gang

By | July 1, 2012

More than simply helping haul out a cell’s garbage, ubiquitin, with its panoply of chain lengths and shapes, marks and regulates many unrelated cellular processes.

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image: Ubiquitin basics

Ubiquitin basics

By | July 1, 2012

Despite its discovery as a protein that seems to show up everywhere, at least in eukaryotic cells, researchers are only beginning to scratch the surface of all of the cellular functions involving ubiquitin. 


image: Forced Feeding

Forced Feeding

By | February 1, 2012

Editor's choice in drug development


image: Come Inside

Come Inside

By | March 1, 2011

Editor's choice in immunology


image: The Genes of Parkinson’s Disease

The Genes of Parkinson’s Disease

By | February 1, 2011

The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.



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