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tag noncoding rna culture disease medicine genetics genomics ecology
The Noncoding Regulators of the Brain
Christie Wilcox, PhD
| Sep 12, 2022
| 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Targeting the Noncoding Genome with CRISPR
Anna Azvolinsky
| Sep 29, 2016
| 4 min read
Two independent groups demonstrate the utility of CRISPR-based techniques to identify regulatory elements that govern disease-linked genes.
Book Excerpt from
Deep Medicine
Eric Topol
| Jul 15, 2019
| 4 min read
In Chapter 10, “Deep Discovery,” author Eric Topol considers the marriage of omics and AI.
2022 Top 10 Innovations
The Scientist
| Dec 12, 2022
| 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
RNA-Seq Reveals Previously Hidden, Genetic DisorderāCausing Mutations
Anna Azvolinsky
| Apr 19, 2017
| 3 min read
Adding RNA sequencing analysis to genomic sequencing helps scientists uncover mutations likely responsible for genetic disorders they might otherwise miss.
The Dark Matter of the Human Proteome
Annie Rathore
| Apr 1, 2019
| 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
Jumping Genes’ Role in Cancer
Diana Kwon
| Mar 1, 2023
| 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.
Antisense Oligonucleotides Cross Rodents’ Blood-Brain Barrier
Abby Olena, PhD
| Aug 18, 2021
| 3 min read
RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.
How an Early Warning Radar Could Prevent Future Pandemics
Amos Zeeberg,
Undark
| Feb 27, 2023
| 8 min read
Metagenomic sequencing can help detect unknown pathogens, but its widespread use faces challenges.
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