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tag noncoding rna genetics genomics evolution developmental biology disease medicine

Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
The Human Genome: RNA Machine
John S. Mattick | Oct 1, 2007 | 7 min read
The Human Genome: RNA Machine Contrary to current dogma, most of the genome may be functional. John S. Mattick Related Articles 1 The idea of "junk DNA" is also based on the assumption that most genetic information is transacted via proteins, an assumption that dates back half a century to a time when the pioneers of molecular biology were studying bacteria, wherein most genes do indeed encode proteins. By contrast, protein coding sequences occupy only ~1.2% of the
MicroRNA evolution put to the test
Jeffrey M. Perkel | Oct 29, 2006 | 4 min read
Two Nature Genetics papers probe evolution and functionality of microRNAs and their target sites
5 images related to stories highlighted in the article, including DNA strand, insect, and dog
Our Favorite Genetics Stories of 2021
Christie Wilcox, PhD | Dec 23, 2021 | 4 min read
Studies The Scientist covered this year illustrate the expanding importance of genetic and genomic research in all aspects of life science, from ecology to medicine.
Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
Multiple Strikes Against Autism
Ruth Williams | Apr 4, 2012 | 3 min read
Scientists discover new autism genes and a non-coding RNA thought to contribute to the disorder.
The dark matter of disease
Hannah Waters | Apr 24, 2011 | 5 min read
Scientists are beginning to unravel how non-coding DNA works across long distances of the genome to influence disease
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Protein Synthesis Enzymes Have Evolved Additional Jobs
Amber Dance | Jun 1, 2020 | 10+ min read
Aminoacyl-tRNA synthetases, which help translate the genetic code into protein, also function in angiogenesis, fat metabolism, and more.
RNA Epigenetics
Gidi Rechavi, Chuan He, and Dan Dominissini | Jan 1, 2016 | 10 min read
DNA isn’t the only decorated nucleic acid in the cell. Modifications to RNA molecules are much more common and are critical for regulating diverse biological processes.

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