There are five steps of autophagosome biogenesis: induction, expansion, vesicle completion, fusion, and cargo degradation. While much has been learned over the past few decades about how this process works, the big question that remains is where the
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Despite years of research, the longstanding mystery of where the autophagosome gets its double lipid bilayers is not much clearer.
A biologist and a physicist collaborate on a decade-long exploration of the physical parameters of membrane traffic in eukaryotic cells.
Institut Curie researchers Bruno Goud, a biologist, and Patricia Bassereau, a physicist, talk about their fruitful, decade-long collaboration exploring the physics of membrane trafficking in a Skype interview conducted by Associate Editor Richard P. Grant.
Lewis Cantley has made a career of turning chemical contaminants into groundbreaking discoveries—including novel lipids, potent inhibitors, and kinases involved in cancer.
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