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tag differentiation evolution cell molecular biology

Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Molecular Biology
The Scientist Staff | Aug 22, 1993 | 2 min read
M. Leid, P. Kastner, R. Lyons, et al., "Purification, cloning and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently," Cell, 68:377-95, 1992. Mark Leid (Oregon State University, Corvallis): "The diverse effects of retinoic acid (RA) on development, cellular growth and differentiation, and homeostasis are mediated by two families of RA receptors that arose independently during evolution and belong to the steroid/thyroid hormone super
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
MOLECULAR BIOLOGY
Paris | Jul 19, 1992 | 1 min read
Michel Philippe (Universite de Rennes, Rennes Cédex, France): "In yeast, two critical points of the cell cycle (Start and G1/S) are regulated by the same protein. This protein, called p34cdc2, is coded by the genes cdc2 in Schizzosaccharomyces pombe and CDC28 in Saccharomyces cerevisiae. By complementation of yeast mutants, proteins from higher eucaryotes homologous to cdc2 have been cloned. Moreover, p34cdc2 has been shown to be one of the main components of the well-known M-phase promotin
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Single-Celled Life Primed to Go Multicellular
Bob Grant | Oct 17, 2016 | 2 min read
The unicellular ancestor of animals may have harbored some of the molecular tools that its many-celled descendants use to coordinate and direct cell differentiation and function, scientists show.
Top 7 in Molecular Biology
Tia Ghose | Nov 1, 2011 | 3 min read
A snapshot of the most highly ranked articles in molecular biology and related areas, from Faculty of 1000
A blood sample containing white and red blood cells.
Enhancing Cell Morphology-Based Analysis
The Scientist and Deepcell | Aug 3, 2023 | 3 min read
Learn how the latest AI-driven technology uses morphology to comprehensively analyze and sort cell populations.
Assessing Differential Gene Expression
Barbara Cunningham | Nov 25, 2001 | 9 min read
As the complete human genome sequence emerges, research shifts from questions of genomics to those of proteomics--determining the function of individual gene products and mapping global gene expression patterns. Gene expression patterns change continually during the course of tissue development and differentiation. The expression of different gene products at any given time within a particular cell defines the cell's characteristics and helps determine how it will react to external stimuli. Alte

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