Mignon Fogarty | Jul 27, 2003 | 7 min read
NETWORKED: (A) Effects of the gal4D+gal perturbation are superimposed on a gene interaction network… Click for larger version (92K) Large-scale biology once conjured images of brute-force genetic screens resulting in collections of mutants. More recently, it has meant genome sequencing on unprecedented scales. But today, as this issue's Hot Papers demonstrate, the leading edge in large-scale biology is proteomics. As in the large-scale efforts of the past, researchers rely on simp