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tag estrogen developmental biology evolution disease medicine cell molecular biology

Environmental Health Institute Blends Toxicology And Molecular Biology
Karen Young Kreeger | May 1, 1995 | 9 min read
Situated equidistant from Raleigh, Durham, and Chapel Hill, N.C.--smack in the middle of the Research Triangle--sits the only National Institutes of Health institutional campus outside of the Washington, D.C., Beltway. The National Institute of Environmental Health Sciences (NIEHS) is currently responsible for nearly 50 percent of all federally funded research on such subjects. It commands a diverse research agenda that covers populations and geographical boundaries far beyond the triangle or t
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
How Groups of Cells Cooperate to Build Organs and Organisms
Michael Levin | Sep 1, 2020 | 10+ min read
Understanding biology’s software—the rules that enable great plasticity in how cell collectives generate reliable anatomies—is key to advancing tissue engineering and regenerative medicine.
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
Targeting Estrogen Receptor-B: A Case Study in Drug Discovery
Jennifer Fisher Wilson | May 18, 2003 | 10+ min read
 Models of estradiol (left) and genistein. For decades, researchers believed that a single estrogen receptor mediated the effects of estrogens in the body. So imagine their surprise when Jan-Åke Gustafsson of the Karolinska Institute in Stockholm announced at a 1996 Keystone symposium the discovery of a second estrogen receptor in the rat prostate. The revelation added unexpected complexity to scientists' understanding of estrogen's biological action. Many attendees scurried back to
Image of someone scratching their skin.
A Chronic Itch: Burrowing Beneath the Skin
Brian S. Kim, MD | Sep 8, 2023 | 9 min read
We have barely scratched the surface of itch science and what it indicates about our health.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Can Destroying Senescent Cells Treat Age-Related Disease?
Katarina Zimmer | Mar 1, 2020 | 10+ min read
A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.

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