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tag synthetic biology ecology microbiology neuroscience immunology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
Environmental Cues Keep CAR T Cells on Track
Aparna Nathan, PhD | May 25, 2021 | 4 min read
Pairing CARs with a synthetic receptor makes T cells more lethal tumor killers.
Contributors
The Scientist Staff | Aug 1, 2011 | 2 min read
Meet some of the people featured in the August 2011 issue of The Scientist.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
Mining Bacterial Small Molecules
L. Caetano M. Antunes, Julian E. Davies and B. Brett Finlay | Jan 1, 2011 | 10 min read
As much as rainforests or deep-sea vents, the human gut holds rich stores of microbial chemicals that should be mined for their pharmacological potential.
Those We Lost in 2019
Ashley Yeager | Dec 30, 2019 | 6 min read
The scientific community said goodbye to Sydney Brenner, Paul Greengard, Patricia Bath, and a number of other leading researchers this year.
Articles Alert
Simon Silver | May 13, 1990 | 7 min read
Department of Microbiology & Immunology University of Illinois Chicago Cosy, Noesy, and HoHaHa! Respectively, these are abbreviations for two-dimensional scalar correlated spectroscopy, two-dimensional nuclear Overhauser enhancement spectroscopy, and Homonuclear Hartmann Hahn transfer experiment - three of the techniques used to study Megasphaera elsdenii. Apparently, we need to learn well the general rules for two-dimensional nuclear magnetic resonance (NMR) determination of atomic conne
Contributors
Diana Kwon | May 1, 2017 | 4 min read
Meet some of the people featured in the May 2017 issue of The Scientist.

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