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tag coronary heart disease disease medicine developmental biology genetics genomics

The dark matter of disease
Hannah Waters | Apr 24, 2011 | 5 min read
Scientists are beginning to unravel how non-coding DNA works across long distances of the genome to influence disease
5 images related to stories highlighted in the article, including DNA strand, insect, and dog
Our Favorite Genetics Stories of 2021
Christie Wilcox, PhD | Dec 23, 2021 | 4 min read
Studies The Scientist covered this year illustrate the expanding importance of genetic and genomic research in all aspects of life science, from ecology to medicine.
The Challenges of Rare-Disease Research
Jyoti Madhusoodanan | Sep 1, 2016 | 8 min read
With few resources and hesitant investors, basic scientists must rely on clinicians, patient advocates, and their own keen eye for biological connections.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Defining Rare Disorders: A Profile of Judith Hall
Anna Azvolinsky | Sep 1, 2019 | 8 min read
By bringing genetics into clinical medicine, the University of British Columbia medical geneticist helped to identify the gene mutations responsible for many rare diseases.
New Light on Fetal Origins of Adult Disease
Ricki Lewis | Oct 29, 2000 | 5 min read
Human prenatal development can be viewed as a program of genetic switches that turn on, in a highly regulated manner, at specific places and times. But a body of evidence is emerging that paints a less hardwired picture, one of responses to environmental challenges fostering changes early on that reverberate decades later, in the guise of cardiovascular disease and diabetes. A symposium at the American Society of Human Genetics annual meeting, held in Philadelphia Oct. 3-7, addressed the fetal o
On Race and Medicine
Keith Norris | Feb 1, 2014 | 4 min read
Until health care becomes truly personalized, race and ethnicity will continue to be important clues guiding medical treatments.
GWAS, psychotic disorder, mood disorder, Q&A, bipolar disorder, schizophrenia, depression, sex differences
Genetic Variants Tied to Sex Differences in Psychiatric Disorders
Amanda Heidt | Mar 31, 2021 | 5 min read
The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Can Genetics Explain Human Behavior?
Bill Sullivan | Sep 1, 2019 | 3 min read
The author of a new book about emerging concepts in human genetics considers the question.

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