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Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Ghosts in the Genome
Oliver J. Rando | Dec 1, 2015 | 10+ min read
How one generation’s experience can affect the next
The Infection-Chronic Disease Link Strengthens
Ricki Lewis | Sep 3, 2000 | 6 min read
Infection" is usually associated with an oozing sore, a bout with the flu, or an outbreak in some exotic place. But infectious organisms lie behind many chronic illnesses too, and an increasingly molecular approach to diagnosis is clarifying some of these relationships. An invited panel discussed "The Infectious Etiology of Chronic Diseases" at the second International Conference on Emerging Infectious Diseases, held in Atlanta July 16-19. Chronic diseases take a huge toll. "In the [United St
Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat
Decoding DNA: New Twists and Turns
The Scientist Marketing Team | Feb 20, 2013 | 6 min read
The Scientist takes a bold look at what the future holds for DNA research, bringing together senior investigators and key leaders in the field of genetics and genomics in this 3-part webinar series.
Who Sleeps?
The Scientist and Jerome Siegel | Mar 1, 2016 | 10+ min read
Once believed to be unique to birds and mammals, sleep is found across the metazoan kingdom. Some animals, it seems, can’t live without it, though no one knows exactly why.
New Molecular Tools Enable Researchers To Correlate Viruses, Diseases
Karen Young Kreeger | Feb 4, 1996 | 7 min read
Viruses, Diseases Author: Karen Young Kreeger Sidebar: Professional Resources for Viral Disease Researchers In the mid- to late 1980s, numerous correlations were discovered between viruses and various types of cancers. For example, Epstein-Barr virus was associated with nasopharyngeal carcinoma and B-cell lymphoma, hepatitis B virus with liver cancer, and human papillomavirus with cervical cancer. Now, a decade later, basic and clinical scientists are finding out that viruses may also play a r
Notebook
Steve Bunk | Nov 7, 1999 | 7 min read
Content Jumping DNA Semen pharming Screening for heart risk Real-time signaling PubSCIENCE starts, PubMedCentral grows When time stands still Shutting down the pump Brain gain JUMPING DNA Mutations aren't transmitted only by inheritance--they can cross species, too, according to recent findings by John F. McDonald, head of the genetics department at the University of Georgia (I.K. Jordan et al., "Evidence for the recent horizontal transfer of long terminal repeat retrotransposon," Proceedings of
Notebook
Eugene Russo | Dec 5, 1999 | 7 min read
Contents Pivotal pump Leptin limbo Clue to obesity Biotech Web site Helping hand Mapping malaria Notebook Pictured above are pigmented bacterial colonies of Deinococcus radiodurans, the most radiation-resistant organism currently known. DEINO-MITE CLEANUP In 1956, investigators discovered a potentially invaluable cleanup tool in an unlikely place. A hardy bacterium called Deinococcus radiodurans unexpectedly thrived in samples of canned meat thought to be sterilized by gamma radiation. The b
Articles Alert
The Scientist Staff | Aug 7, 1988 | 8 min read
The Scientist has asked a group of experts to periodically comment upon recent articles that they have found noteworthy. Their selections, presented here in every issue, we neither endorsements of content nor the result of systematic searching. Rather, they are personal choices of articles they believe the scientific community as a whole may also find interesting. Reprints of any articles cited here may be ordered through The Genuine Article 3501 Market St., Philadelphia, Pa. 19104, or by telep

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