With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.

To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.

New ways to search for druggable RNAs and matching small molecules

The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.

Suppliers of Whole-organism cDNA Libraries Suppliers of Tissue-specific cDNA Libraries The questions of gene function, interaction, and regulation are central to the science of molecular biology. Despite the myriad of new technologies, products, and techniques produced by the genomics revolution, some old standards remain just as useful as ever. One such technology is the cDNA (complementary DNA) library. The sheer number of companies offering premade and custom cDNA libraries and products th

Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.

Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.

Graphic: Cathleen Heard The boy had the classic symptoms of acute leukemia--low blood counts and tumor cells circulating in his bloodstream. But the diagnosis was tentative because the tumor cells looked atypical for leukemia. So doctors extracted RNA from the cells, made cDNAs from the RNA, and incubated the cDNAs with a chip bearing thousands of single-stranded gene fragments on its glass surface. The hybridization pattern suggested, surprisingly, that the boy had a muscle tumor. After confirm

The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.