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tag space shuttle genetics genomics immunology

Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
Conceptual image of a person's brain with a cluster of cells inside
Is the Immune System to Blame for Schizophrenia?
Diana Kwon | Apr 18, 2022 | 10+ min read
Several lines of evidence suggest that targeting the body’s defense pathways might help treat a subset of people with the psychiatric disorder. But many open questions remain.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
A Movable Defense
Eugene V. Koonin and Mart Krupovic | Jan 1, 2015 | 10 min read
In the evolutionary arms race between pathogens and hosts, genetic elements known as transposons are regularly recruited as assault weapons for cellular defense.
Exosomes Make Their Debut in Plant Research
Amanda Keener | Feb 1, 2019 | 10+ min read
A growing branch of research on how plants use exosomes to interact with their environment is opening up a new field of plant biology.
Neoantigens Enable Personalized Cancer Immunotherapy
Stephen P. Schoenberger and Ezra Cohen | Apr 1, 2017 | 9 min read
Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
Roll-Your-Own Microarrays
Jim Kling | Jan 6, 2002 | 3 min read
CDNA microarrays hold great promise for characterizing disease and performing genetic studies, but they're not exactly an out-of-the-box technology just yet. Often the scientists must prepare their own chips. Yet, this process is limited by the amount of space on the array itself—forcing researchers to make choices about which genes to include in their sample. Clinical microarray applications are further limited by the availability of sufficient cell numbers for testing purposes. Illumina
Resistant to Failure
Cristina Luiggi | Feb 28, 2011 | 3 min read
A Duke University researcher survives a sticky situation at a federal research institution to make major strides in determining the genetic roots of Staphylococcus aureus antibiotic resistance.

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