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image: Replication Complications

Replication Complications

By | January 18, 2017

An initiative to replicate key findings in cancer biology yields a preliminary conclusion: it’s difficult.

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Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.

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A team of scientists was unable to replicate controversial, high-profile findings published in 2011.

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image: Exploring the Epigenetics of Ethnicity

Exploring the Epigenetics of Ethnicity

By | January 11, 2017

Researchers attempt to estimate how much of the human genome’s methylation patterns can be attributed to genetic ancestry.

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Children born to obese parents are at increased risk of failing motor development and cognitive tests, according to an NIH-led study.

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image: Methylation Maestro

Methylation Maestro

By | January 1, 2017

After initially discovering that DNA methylation represses transcription, Howard Cedar continues to explore how the epigenetic mark regulates gene expression.

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image: Transgenerational Epigenetics Prepares Plants for Drought

Transgenerational Epigenetics Prepares Plants for Drought

By | January 1, 2017

Plants grown in dry soil produce offspring that are hardier in drought conditions, and DNA methylation appears responsible. 

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image: Mouse Immunology Paper Retracted

Mouse Immunology Paper Retracted

By | December 16, 2016

A finding of misconduct spurs the retraction of a Science paper claiming to have identified a protein in mice that boosted immunity to both viruses and cancer.

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image: Induced Pluripotent Stem Cells Show Signs of Donor Age

Induced Pluripotent Stem Cells Show Signs of Donor Age

By | December 12, 2016

iPSCs created through the reprogramming of human somatic cells retain genomic marks of the donor’s age.

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image: Video: Watch Cells Crawl To Firmer Ground

Video: Watch Cells Crawl To Firmer Ground

By | December 11, 2016

This collective migration, called durotaxis, depends on which cells get the best grip on a surface.

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