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In Their Earliest Days, Embryos Record Their Environments
In Their Earliest Days, Embryos Record Their Environments
Methylation patterns at so-called metastable epialleles in the genome stamp a memory into each of our cells.
In Their Earliest Days, Embryos Record Their Environments
In Their Earliest Days, Embryos Record Their Environments

Methylation patterns at so-called metastable epialleles in the genome stamp a memory into each of our cells.

Methylation patterns at so-called metastable epialleles in the genome stamp a memory into each of our cells.

epigenetics, developmental biology

New Techniques Detail Embryos’ First Hours and Days
Jef Akst | Dec 1, 2017 | 10+ min read
New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.
Infographic: How Embryos Take Control of Their Own Development
Jef Akst | Nov 30, 2017 | 3 min read
The switch from maternal factors involves dynamic reprogramming of the zygotic genome.
Leaving an Imprint
Anna Azvolinsky | Aug 1, 2015 | 8 min read
Among the first to discover epigenetic reprogramming during mammalian development, Wolf Reik has been studying the dynamics of the epigenome for 30 years.
Mimicry Muses
Mary Beth Aberlin | Aug 1, 2015 | 2 min read
The animal world is full of clever solutions to bioengineering challenges.
Mr. Epigenetics
The Scientist | Jul 31, 2015 | 1 min read
Meet Wolf Reik, August Profilee and Babraham Institute director of research.
From Many, One
Elena E. Giorgi | Apr 1, 2015 | 10+ min read
Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?
Unmasking Secret Identities
Kate Yandell | Feb 1, 2014 | 9 min read
A tour of techniques for measuring DNA hydroxymethylation
Epigenetics of Embryonic Stem Cells
Kate Yandell | May 14, 2013 | 2 min read
Researchers track DNA modifications and gene expression in stem cells as they differentiate.
Pluripotent Until Needed
Beth Marie Mole | Apr 1, 2013 | 7 min read
Microarrays help keep induced pluripotent stem cell lines in check, from start to finish.
Home Cookin’
Hayley Dunning | Oct 1, 2012 | 4 min read
Laboratory-raised populations of dung beetles reveal a mother's extragenetic influence on the physiques of her sons.
Beyond Nature vs. Nurture
Darlene Francis and Daniela Kaufer | Oct 1, 2011 | 3 min read
Researchers studying differences in how individuals respond to stress are finding that genes are malleable and environments can be deterministic.
Lab-Grown Sperm
Cristina Luiggi | Aug 4, 2011 | 3 min read
Healthy mice are born from germ cell precursors grown in vitro.
First, Do No Harm…
Jim Woodgett | Jun 9, 2011 | 5 min read
Is DNA damage an inevitable consequence of epigenetic reprogramming?
The Footprints of Winter
Ralf Müller and Justin Goodrich | Mar 1, 2011 | 4 min read
Epigenetic marks laid down during the cold months of the year allow flowering in spring and summer.
Imprinting Diversity
Cristina Luiggi | Feb 28, 2011 | 3 min read
Joachim Messing talks about how genomic imprinting may be a strong driver of diversity.
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