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tag infrastructure evolution culture developmental biology

Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
On the Fast Track in Functional Proteomics
A. J. S. Rayl | Apr 1, 2001 | 8 min read
Graphic: Leza Berardone Researchers in Canada and Denmark are employing mass spectrometry, three-dimensional tissue biology, and supercomputing to blaze a trail in functional proteomics research. In the process, they're putting their company, MDS Proteomics Inc., on the fast track in the latest race to develop new drug targets and eventually better treatments for all kinds of diseases. By using this combination of technologies, MDS Proteomics is accelerating the process of identifying, analyzin
How to Create a Successful Fish Tale?
A. J. S. Rayl | Aug 19, 2001 | 10+ min read
More than 80 percent of the planet's living organisms exist only in aquatic ecosystems. Some may harbor secrets to human origins, and clues, treatments--perhaps even cures--for human disease. Some are critical bioindicators that portend the health of the biosphere. Yet, overall, scientists know little about the biochemical processes of these life forms. The vast, rich knowledge within the oceans and freshwater systems on Earth remains virtually untapped, because in the world of biological resear
Sequencing the Tree of Life
Anna Azvolinsky | Apr 24, 2014 | 7 min read
Charting the progress of the various large-scale genome-sequencing projects as researchers working separately on their chosen species begin to pool analytical resources
What Makes a Human?
John Mattick(j.mattick@imb.uq.edu.au) | Feb 27, 2005 | 5 min read
Sometimes it is hard to see the forest for the trees.
Researchers Receiving MacArthur Fellowships Demonstrate 'Capacity To Make A Difference'
Bruce Anderson | Sep 14, 1997 | 6 min read
PRIZE WITH A PRICE: Science historian Peter Galison has taken some ribbing from his family since being named a MacArthur fellow. One could almost pity Peter Galison. A historian of science at Harvard University, Galison is one of seven members of the scientific community among the 23 recipients of this year's John D. and Catherine T. MacArthur Foundation Fellowships. The coveted five-year awards provide unrestricted support plus health insurance to talented individuals, with no reports or proj
Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat
Genetic Parasites and a Whole Lot More
Barry Palevitz | Oct 15, 2000 | 10+ min read
Photo: Ori Fragman, Hebrew University Hordeum spontaneum, the plant studied for BARE-1 retroelements. With genome sequences arriving almost as regularly as the morning paper, the public's attention is focused on genes--new genes to protect crops against pests; rogue genes that make bacteria resistant to antibiotics; faulty genes that, if fixed, could cure diseases such as muscular dystrophy. What many people don't realize is that genes account for only part of an organism's DNA, and in many c

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