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tag toll like receptor culture

Influenza pays its toll
Edyta Zielinska | Jul 1, 2007 | 2 min read
Credit: © IMA / Photo Researchers, Inc." /> Credit: © IMA / Photo Researchers, Inc. The paper: L. Guillot et al., "Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus," J. Biol Chem, 280: 5571-80, 2005. (Cited in 82 papers) The finding: Mustapha Si-Tahar at Inserm in Paris and colleagues showed that toll like receptor 3 (TLR3) plays a prominent role i
Black and gold sketch of Katalin Karikó and Drew Weissman.
Nobel Prize for mRNA Vaccines
Danielle Gerhard, PhD | Oct 2, 2023 | 5 min read
Katalin Karikó and Drew Weissman received this year’s Physiology or Medicine award for their work on RNA biology and mRNA-based vaccines.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
One Receptor, Two Ligands, Different Responses
Ruth Williams | Aug 30, 2016 | 3 min read
Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 
Experimental MERS Treatments Target Host Cell Receptor
Ashley Yeager | Mar 30, 2017 | 4 min read
Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
Immunologists Take Home Nobel
Rachel Nuwer | Oct 3, 2011 | 4 min read
The Nobel Assembly announced today that three researchers in the field of immunology will share the 2011 Prize in Physiology or Medicine.
Glial Ties to Persistent Pain
Mark R. Hutchinson | Jan 1, 2018 | 10 min read
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.
The Scientist Staff | Mar 19, 2024

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