The Scientist

» preclinical

Most Recent

image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

0 Comments

image: RNA Vaccine for Zika Shows Promise

RNA Vaccine for Zika Shows Promise

By | February 2, 2017

Researchers use modified messenger RNA to produce a vaccine that protected mice and nonhuman primates from infection.

1 Comment

image: The Trouble With Sex in Science

The Trouble With Sex in Science

By | August 9, 2016

Researchers argue for the consideration of hormones and sex chromosomes in preclinical experiments.

0 Comments

image: TS Picks: February 11, 2016

TS Picks: February 11, 2016

By | February 11, 2016

Reproducibility edition

0 Comments

image: In Situ Antibodies

In Situ Antibodies

By | February 2, 2016

Compared with systemic injections, localized antibody therapies may be more effective for some indications.

2 Comments

image: The Sounds of Silence

The Sounds of Silence

By | September 1, 2015

Science-based tinnitus therapeutics are finally coming into their own.

3 Comments

image: Organ-on-a-Chip Gets Big Pharma Boost

Organ-on-a-Chip Gets Big Pharma Boost

By | June 18, 2015

Johnson & Johnson agrees to use Emulate’s blood-clot device in three of its preclinical drug programs.

0 Comments

image: Ebola Vaccines Protect Monkeys

Ebola Vaccines Protect Monkeys

By | April 9, 2015

Two new Ebola vaccine candidates prove safe and effective against the virus in macaques, a study shows.

0 Comments

image: NIH to Close Sex Gap in Preclinical Research

NIH to Close Sex Gap in Preclinical Research

By | May 15, 2014

The funding agency will require grant applicants to address sex balance in all future cell and animal studies.

0 Comments

image: Opinion: Pairing Discovery with Regulatory Rigor

Opinion: Pairing Discovery with Regulatory Rigor

By | May 13, 2014

To move cell-based therapies into the clinic, academic researchers may benefit by consulting researchers outside of academia and the biopharma industry.

0 Comments

Popular Now

  1. UC Berkeley Receives CRISPR Patent in Europe
    Daily News UC Berkeley Receives CRISPR Patent in Europe

    The European Patent Office will grant patent rights over the use of CRISPR in all cell types to a University of California team, contrasting with a recent decision in the U.S.

  2. What Budget Cuts Might Mean for US Science
    News Analysis What Budget Cuts Might Mean for US Science

    A look at the historical effects of downsized research funding suggests that the Trump administration’s proposed budget could hit early-career scientists the hardest.  

  3. Opinion: On “The Impact Factor Fallacy”
  4. Unstructured Proteins Help Tardigrades Survive Desiccation
Business Birmingham