Irving Weissman and Michael Clarke | Apr 1, 2006 | 4 min read
FEATUREThe Ecology of Tumors Leukemia and Cancer Stem Cells BY IRVING WEISSMAN AND MICHAEL CLARKECancers and normal tissue stem cells have much in common: Both have self-renewal capacity, and both develop into differentiated progeny. But do true cancer stem cells exist? We believe that they do and that this realization will have a major impact on the understanding and treatment of cancers. Putative cancer stem cells can be recognized by three attr