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image: Replication Complications

Replication Complications

By | January 18, 2017

An initiative to replicate key findings in cancer biology yields a preliminary conclusion: it’s difficult.

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Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.

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A team of scientists was unable to replicate controversial, high-profile findings published in 2011.

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image: Exploring the Epigenetics of Ethnicity

Exploring the Epigenetics of Ethnicity

By | January 11, 2017

Researchers attempt to estimate how much of the human genome’s methylation patterns can be attributed to genetic ancestry.

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image: Image of the Day: Feeding Time

Image of the Day: Feeding Time

By | January 10, 2017

Scientists are working to improve the abilities of therapeutic antibodies to flag cancer cells (orange) for destruction by macrophages (blue).  

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Contributors

By | January 1, 2017

Meet some of the people featured in the January 2017 issue of The Scientist.

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image: Newly Found White Blood Cell Withstands Chemotherapy

Newly Found White Blood Cell Withstands Chemotherapy

By | January 1, 2017

Vaccine-induced macrophages open a new realm of study into remodeling the immune system to reduce the risk of infections during cancer treatment.

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image: Pharma Redo

Pharma Redo

By | January 1, 2017

Steve Braun of Cures Within Reach, a nonprofit focused on breathing new life into old medicines, describes the potential benefits of drug repurposing.

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Oncologists have raised concerns about a mouse study that suggests the vaccine for human papillomavirus could cause brain damage.

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image: Video: Watch Cells Crawl To Firmer Ground

Video: Watch Cells Crawl To Firmer Ground

By | December 11, 2016

This collective migration, called durotaxis, depends on which cells get the best grip on a surface.

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