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tag drug safety culture evolution

Cas9 enzyme
Molecular Glue ‘Shreds’ Cas9 and Enables a New Form of CRISPR Control
Ida Emilie Steinmark, PhD | Apr 26, 2023 | 3 min read
In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.
Abcam’s new premium-grade bioactive proteins, for drug discovery, development and manufacturing
Abcam | Nov 12, 2020 | 1 min read

Abcam’s new premium-grade bioactive proteins are highly-active growth factors and cytokines manufactured and designed to meet the specific needs of cell culture, including cell and gene therapy and regenerative medicine. 

Capsule Reviews
Annie Gottlieb | Sep 1, 2012 | 3 min read
Wired for Story, Dreamland, Homo Mysterious, and Vagina
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
monoclonal antibody antibodies sars-cov-2 covid-19 coronavirus pandemic eli lilly receptor binding domain spike protein
First Antibody Trial Launched in COVID-19 Patients
Katarina Zimmer | Jun 2, 2020 | 8 min read
In record time, scientists have gone from harvesting antibodies against SARS-CoV-2 from survivors of coronavirus infections to testing the antibodies’ safety as a drug in humans.
Chloroquine Protects Against Zika In Vitro
Marcia Triunfol | May 12, 2016 | 3 min read
The antimalarial drug reduces the number of infected Vero and human brain microvascular endothelial cells—among other cell types—in culture, researchers report in a preprint.
microbiome drugs
How the Microbiome Influences Drug Action
Shawna Williams | Jul 15, 2019 | 10+ min read
Through their effects on metabolism and immunity, bacteria in the gut affect whether medications will be effective for a given patient.
Protein Synthesis Enzymes Have Evolved Additional Jobs
Amber Dance | Jun 1, 2020 | 10+ min read
Aminoacyl-tRNA synthetases, which help translate the genetic code into protein, also function in angiogenesis, fat metabolism, and more.
2022 Top 10 Innovations&nbsp;
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.

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