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tag drug safety developmental biology ecology

Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.
An illustration of flowers in the shape of the female reproductive tract
Uterus Transplants Hit the Clinic
Jef Akst | Aug 1, 2021 | 10+ min read
With human research trials resulting in dozens of successful deliveries in the US and abroad, doctors move toward offering the surgery clinically, while working to learn all they can about uterine and transplant biology from the still-rare procedure.
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The Scientist | Jun 23, 2011 | 4 min read
A selection of comments from our readers.
Deciphering How the Sexes Think
Karen Young Kreeger | Jan 20, 2002 | 7 min read
Editor's Note: This is the second article in a series on sex-based differences in the biology of males and females. Future articles in the series will cover sex-based differences in genetics, autoimmunity, and drug metabolism. Stereotypes aside, women and men do process information in singular ways. In the past, tests that tried to pinpoint those variations were fraught with inconsistencies and irregularities. But now, by studying the brain itself, researchers are learning that the sexes use dif
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
Centrifuge Improvements Put New Spin On A Laboratory Workhorse
Howard Goldner | Mar 5, 1995 | 7 min read
A true laboratory workhorse, the centrifuge has been an essential part of most biological labs for many years. Using centrifugal force obtained by spinning experimental samples at high revolutions per minute (rpm), the device functions as a preparative method to separate various sample components, within minutes, for further treatment. Ultracentrifugation is an even more powerful technique that is used in analytical studies involving the characterization of and interactions between biological m
Week in Review: January 30–February 3
Joshua A. Krisch | Feb 2, 2017 | 3 min read
March for science debate; an RNA vaccine for Zika; responses to Trump’s immigration order; native habitat restoration; views from local March for Science organizers; artificial cells and the Turing test
Labs in Texas Batten Down the Hatches
Shawna Williams and Bob Grant | Aug 25, 2017 | 4 min read
As Hurricane Harvey approaches land, researchers wait to see if their preparations will protect their experiments.

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