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image: Replication Complications

Replication Complications

By | January 18, 2017

An initiative to replicate key findings in cancer biology yields a preliminary conclusion: it’s difficult.

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Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.

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A team of scientists was unable to replicate controversial, high-profile findings published in 2011.

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image: Drug Approval Timeline Same as 20 Years Ago

Drug Approval Timeline Same as 20 Years Ago

By | January 9, 2017

A report finds that new medications still take about 12 years to go from patent to patient.

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image: Pharma Redo

Pharma Redo

By | January 1, 2017

Steve Braun of Cures Within Reach, a nonprofit focused on breathing new life into old medicines, describes the potential benefits of drug repurposing.

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image: Repurposing Existing Drugs for New Indications

Repurposing Existing Drugs for New Indications

By | January 1, 2017

An entire industry has sprung up around resurrecting failed drugs and recycling existing compounds for novel indications.

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image: Infographic: Repurposing Strategies

Infographic: Repurposing Strategies

By | January 1, 2017

Novel uses for existing and failed drugs may save companies time and money in bringing new therapeutics to market.

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image: Mouse Immunology Paper Retracted

Mouse Immunology Paper Retracted

By | December 16, 2016

A finding of misconduct spurs the retraction of a Science paper claiming to have identified a protein in mice that boosted immunity to both viruses and cancer.

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image: Video: Watch Cells Crawl To Firmer Ground

Video: Watch Cells Crawl To Firmer Ground

By | December 11, 2016

This collective migration, called durotaxis, depends on which cells get the best grip on a surface.

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Scientists present evidence of bacteria-driven mating in flagellate eukaryotes at the American Society for Cell Biology annual meeting.

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