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Q8W3K0, listed in the DeepMind database as a potential plant disease resistance protein from Arabidopsis thaliana
Predictions of Most Human Protein Structures Made Freely Available
Lisa Winter | Jul 23, 2021 | 3 min read
The AlphaFold program from AI firm DeepMind has amassed a huge database of protein structures from humans and model organisms.
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blue and white sign for the entrance to the FDA that says U.S. Department of Health and Human Services Food and Drug Administration
Biogen’s Alzheimer’s Drug Gets FDA Approval, Mixed Reviews
Kerry Grens | Jun 7, 2021 | 2 min read
A lackluster performance in clinical trials of the monoclonal antibody aducanumab has left some experts unconvinced of its benefit.
A black line drawing of a mother putting a face mask on a child with a white background
SARS-CoV-2 Antigens Leaking from Gut to Blood Might Trigger MIS-C
Alejandra Manjarrez, PhD | Jun 3, 2021 | 4 min read
Researchers find traces of SARS-CoV-2 in the stool and blood of kids with the post–COVID-19 inflammatory disorder, and signs of increased intestinal permeability.
A microscopy image of a mouse brain that shows the lymphatic system in bright purple and pink
Brain’s Lymphatic System Tied to Alzheimer’s Symptoms in Mice
Amanda Heidt | May 4, 2021 | 5 min read
A dysfunctional lymphatic system, described as a clogging of the brain’s sink, may explain why immunotherapies fail in some Alzheimer’s patients.
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Rachael Moeller Gorman | Apr 1, 2021 | 10+ min read
Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.
Eli Lilly Claims New Drug Can Slow Alzheimer’s-Related Decline
Lisa Winter | Mar 16, 2021 | 2 min read
Patients who received the drug fared better cognitively and functionally than those taking placebo, but still experienced losses in performance.
Gene Therapy for Sickle Cell Not Linked to Cancer, Bluebird Finds
Lisa Winter | Mar 11, 2021 | 2 min read
Clinical trials were halted after the treatment’s vector that ferries in the healthy genetic sequence was identified in the genome of a patient’s cancer cells.
regeneron monoclonal antibody sars-cov-2 covid-19 pandemic coronavirus neutralization b.1.351 variant south africa REGN10987 casirivimab and REGN10933 imdevimab
Regeneron Cocktail Stumbles Against SARS-CoV-2 Variant in Vitro
Marcus A. Banks | Mar 1, 2021 | 3 min read
A treatment of two monoclonal antibodies against SARS-CoV-2 is ninefold less effective in the lab against the B.1.351 variant than against the dominant version of the virus.
SARS-CoV-2, COVID-19, coronavirus, pandemic, virus, vaccine, vaccination, outbreak, infectious disease, Johnson & Johnson, Moderna, Pfizer, drug development
One-Shot COVID-19 Vaccine Prevents Severe Disease
Asher Jones | Jan 29, 2021 | 2 min read
Johnson & Johnson’s vaccine is less effective at preventing COVID-19 than other approved vaccines are, but experts say it could still be an important tool in curbing the pandemic.
The Promise of Scientific Partnerships with People on the Spectrum
Laura Dattaro, Spectrum | Jan 18, 2021 | 10+ min read
Five collaborations involving autistic scientists and experts are advancing autism research, from lending support for theories of the condition to shoring up trials of new treatments.
covid-19 coronavirus sars-cov-2 pandemic tocilizumab sarilumab
UK Approves Arthritis Drugs for Critically Ill COVID-19 Patients
Asher Jones | Jan 11, 2021 | 2 min read
The immunosuppressive drugs tocilizumab and sarilumab improved survival and recovery time of intensive care COVID-19 patients, according to a preprint.
images related to COVID research
What’s Ahead for SARS-CoV-2 Research in 2021
Shawna Williams | Jan 8, 2021 | 5 min read
From new treatments to an investigation into the virus’s origins, here are some of the developments we can expect this year.
a graphic with free-floating puzzle pieces connected in a network
Book excerpt from The Puzzle Solver
Tracie White | Jan 5, 2021 | 4 min read
In Chapter 3, “The Adventure,” author Tracie White meets Whitney Dafoe, a young man imprisoned by a chronic disease.
Opinion: Emergency Use Authorizations Are a Threat to Science 
Kevin J. Tracey and Christina Brennan | Dec 1, 2020 | 4 min read
As COVID-19 therapies get emergency-use green lights, the Biden administration must organize a therapeutic review board to help identify what’s working and what’s not.
Infographic: How Vaccines Train Innate Immunity
Shawna Williams | Nov 1, 2020 | 1 min read
A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.
A Challenge Trial for COVID-19 Would Not Be the First of Its Kind
Jef Akst | Oct 8, 2020 | 9 min read
Although scientists debate the ethics of deliberately infecting volunteers with SARS-CoV-2, plenty of consenting participants have been exposed to all sorts of pathogens in prior trials.
Antibody-Based Drug May Reduce COVID-19 Hospitalizations: Study
Lisa Winter | Sep 17, 2020 | 2 min read
Eli Lilly reports a 72 percent reduction in hospitalization risk among patients who received its monoclonal antibody compared to those who received a placebo.
New Drug Combo for ALS Slows Decline in Small Clinical Study
Jef Akst | Sep 3, 2020 | 3 min read
After six months, patients with fast-progressing amyotrophic lateral sclerosis who had received the experimental treatment had less loss of function than those who received a placebo.
Coronavirus Closeup, 1964
Ashley Yeager | Sep 1, 2020 | 3 min read
Electron microscopy revealed that a deadly disease of birds was not a form of flu, but a different type of virus entirely.
a bag of plasma ready to be delivered by IV
Doctors Forge Ahead with Plasma for COVID-19, Benefits Uncertain
Shawna Williams | Aug 14, 2020 | 2 min read
Researchers say the popularity of convalescent plasma makes it more difficult to gather high-quality data on its efficacy.
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