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tag artificial selection cell molecular biology ecology immunology microbiology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
microbiome
Do Commensal Microbes Stoke the Fire of Autoimmunity?
Amanda B. Keener | Jun 1, 2019 | 10+ min read
Molecules produced by resident bacteria and their hosts may signal immune cells to attack the body’s own tissues.
Biological Terrorism
Jennifer Fisher Wilson | Nov 11, 2001 | 8 min read
One warning came in black-and-white in 1993: A U.S. Congressional Office of Technology Assessment report projected that releasing 100 kilograms of aerosolized anthrax spores upwind of the U.S. capital could kill between 130,000 and 3 million people-a lethality at least matching that of a hydrogen bomb. Last year, a U.S. Justice Department exercise revealed that discharging pneumonic plague in Denver could create 3,700 or more cases, with an estimated 950 or more deaths within a week.1 Then, acco
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
Updated Sept 1
coronavirus pandemic news articles covid-19 sars-cov-2 virology research science
Follow the Coronavirus Outbreak
The Scientist | Feb 20, 2020 | 10+ min read
Saliva tests screen staff and students at University of Illinois; Study ranks species most susceptible to SARS-CoV-2 infection; COVID-19 clinical trials test drugs that inhibit kinin system
Bacteria Harbor Geometric “Organelles”
Amber Dance | Dec 1, 2018 | 10+ min read
Microbes, traditionally thought to lack organelles, get a metabolic boost from geometric compartments that act as cauldrons for chemical reactions. Bioengineers are eager to harness the compartments for their own purposes.
Targeting Antibiotic-Resistant Bacteria with CRISPR and Phages
Anna Azvolinsky | May 18, 2015 | 3 min read
Researchers develop a CRISPR-based, two-phage system that sensitizes resistant bacteria to antibiotics and selectively kills any remaining drug-resistant bugs. 
An Ocean of Viruses
Joshua S. Weitz and Steven W. Wilhelm | Jul 1, 2013 | 10+ min read
Viruses abound in the world’s oceans, yet researchers are only beginning to understand how they affect life and chemistry from the water’s surface to the sea floor.
Panning for T-cell Gold
Mark Davis | Jul 18, 2004 | 5 min read
A COMPLICATED UNION:Image redrawn from Ann Rev Biochem, 72:717–42, 2003Antigens bound by major histocompatibility complex (MHC) molecules interact with T-cell receptors (TCRs) at the heart of the interface for T-cell recognition. But, many other players are involved. Massive polyvalency within this confined space may compensate for low-affinity receptors, giving added sensitivity.In some ways, science resembles gold mining: Eager practitioners congregate around rich veins of discovery whil
illustration of a mitochondrian inside a cell
Could Dad’s Mitochondrial DNA Benefit Hybrids?
Alejandra Manjarrez, PhD | Jan 20, 2022 | 7 min read
Studies have found that organisms can inherit mitochondria from male parents in rare instances, and both theoretical and experimental work hint that this biparental inheritance is more than just a fluke.

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