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tag artificial selection evolution immunology culture

Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Articles Alert
Simon Silver | Jul 8, 1990 | 7 min read
The Scientist has asked a group of experts to comment periodically upon recent articles that they have found noteworthy. Their selections, presented herein every issue, are neither endorsements of content nor the result of systematic searching. Rather, the list represents personal choices of articles the columnists believe the scientific community as a whole may also find interesting. Reprints of any articles cited here may be ordered through The Genuine Article, 3501 Market St., Philadelphia,
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018 | 10+ min read
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Automated Colony Pickers Evolve
Helen Dell(hdell@the-scientist.com) | Jul 3, 2005 | 6 min read
Everyone knows that the first genome sequencing projects took years of work and represent the combined product of tens of thousands of individual fragments.
The Institute Different
Steve Bunk | Feb 18, 2001 | 9 min read
Courtesy Santa Fe InstituteThe Santa Fe Institute, situated in the hills above Santa Fe, N.M. Even its interior design serves the unusual purpose of the Santa Fe Institute (SFI). At the top of a winding drive on the outskirts of the New Mexico capital that calls itself "the city different," SFI occupies a 1950s hacienda defined by three descending "pods." First is reception and administration. Second is a community area, full of comfortable furniture, with big views of the city and mountains. C
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
Genetic Parasites and a Whole Lot More
Barry Palevitz | Oct 15, 2000 | 10+ min read
Photo: Ori Fragman, Hebrew University Hordeum spontaneum, the plant studied for BARE-1 retroelements. With genome sequences arriving almost as regularly as the morning paper, the public's attention is focused on genes--new genes to protect crops against pests; rogue genes that make bacteria resistant to antibiotics; faulty genes that, if fixed, could cure diseases such as muscular dystrophy. What many people don't realize is that genes account for only part of an organism's DNA, and in many c
Deliberating Over Danger
The Scientist | Apr 1, 2012 | 10+ min read
The creation of H5N1 bird flu strains that are transmissible between mammals has thrown the scientific community into a heated debate about whether such research should be allowed and how it should be regulated.
All's Well that Ends Well: A Profile of Specialty Microwell Plates
Brent Johnson | Sep 26, 1999 | 10+ min read
Date: September 27, 1999Table of Specialty Microplates The story of the microplate is one of those tales of history that either has been forgotten or was never clearly understood. According to Barry Lazar of Dynex Technologies, formerly Dynatech Laboratories, the origin of what is now commonly referred to by Dynex's registered trademark of Microtiter plates began with Gyola Takatsy, a Hungarian-born scientist who was trying to scale down serology tests. His first prototype became available in 1

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