With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

Edited by: Neeraja D. Sankaran R.M. Chicz, R.G. Urban, J.C. Gorga, D.A.A. Vignali, W.S. Lane, J.L. Strominger, "Specificity and promiscuity among naturally processed peptides bound to HLA-Dr alleles," Journal of Experimental Medicine, 178:27-47, 1993. (Cited in 107 publications through January 1995) Comments by Roman M. Chicz,department of molecular and cellular biology, Harvard University One of the most important findings in this article, according to its authors, was the observation of pr

Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.

We have barely scratched the surface of itch science and what it indicates about our health.

Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.

This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.

George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

The Scientist spoke with Jonathan Kagan about his idea that immune cells respond to “errors” made by unsuccessful pathogens, not the pathogens themselves.

Studying the earliest events in visual development, Carla Shatz has learned the importance of looking at one’s data with open eyes—and an open mind.

Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.