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tag microscope evolution genetics genomics neuroscience microbiology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Spores of Fusarium xylarioides
Researchers Resurrect Coffee-Destroying Fungus—to Study It
Chloe Tenn | Jan 4, 2022 | 4 min read
Comparing the genomes of modern pathogens with those of cryopreserved strains from several decades ago shed light on the evolution of coffee wilt disease outbreaks in Africa.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
green algae, phytoplankton, giant virus, genetics & genomics, endogenization, evolution, diversity, eukaryote
Giant Viruses Can Integrate into the Genomes of Their Hosts
Amanda Heidt | Nov 19, 2020 | 4 min read
Rather than introducing small chunks of DNA as other viruses do, some giant viruses can contribute more than 1 million base pairs to a host’s genome, broadening the ways in which viruses may shape eukaryote evolution.
Metal shelves densely packed with preserved tissue specimens of various sizes, all suspended in glass containers.
Evolution of 1918 Flu Virus Traced from Century-Old Samples
Dan Robitzski | May 10, 2022 | 5 min read
The work reveals that the pandemic flu was likely the direct predecessor of the seasonal H1N1 flu that circulated for decades.

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