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image: Book Excerpt from <em>p53</em>

Book Excerpt from p53

By | April 1, 2015

In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.

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image: Professional Marksman

Professional Marksman

By | April 1, 2015

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.

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image: Setbacks and Great Leaps

Setbacks and Great Leaps

By | April 1, 2015

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

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image: Two-Faced RNAs

Two-Faced RNAs

By | April 1, 2015

The same microRNAs can have opposing roles in cancer.

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image: Resisting Cancer

Resisting Cancer

By | April 1, 2015

If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.

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image: The Origins of Oversized Chromosomes

The Origins of Oversized Chromosomes

By | November 12, 2014

Researchers reconstruct the formation of the giant neochromosomes that contribute to some cancers.

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image: A Cancer-Heart Disease Link

A Cancer-Heart Disease Link

By | December 22, 2011

Mutations known to increase the risk of developing ovarian and breast cancer may also make carriers susceptible to heart failure.

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image: News from Cell

News from Cell

By | December 9, 2011

Some of the highlights from this year’s American Society for Cell Biology meeting, held earlier this week

3 Comments

image: Myc, Nicked

Myc, Nicked

By | January 1, 2011

Editor's Choice in Developmental Biology

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