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Adding RNA sequencing analysis to genomic sequencing helps scientists uncover mutations likely responsible for genetic disorders they might otherwise miss.

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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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image: Infographic: Single-Cell CRISPR Screens

Infographic: Single-Cell CRISPR Screens

By | March 1, 2017

See how two new methods track responses to unique genetic manipulations in numerous individual cells in parallel.

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Researchers solve the mystery of 15-year-old mutant ferns with disrupted sex determination.

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image: Noncoding RNAs Not So Noncoding

Noncoding RNAs Not So Noncoding

By | June 1, 2016

Bits of the transcriptome once believed to function as RNA molecules are in fact translated into small proteins.

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image: Aneuploid Responses

Aneuploid Responses

By | May 1, 2016

A recent exchange of papers is divided over the evidence for compensatory gene expression among wild strains of aneuploid yeast.

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image: Scaling to Singles

Scaling to Singles

By | May 1, 2016

Tips for tracing transcription in individual cells

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image: Detecting Lyme Early

Detecting Lyme Early

By | February 12, 2016

Two new methods could help researchers to diagnose Lyme disease earlier than with existing tests.

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image: Gene Expression in a Drop

Gene Expression in a Drop

By | August 1, 2015

Tens of thousands of individual cells can have their transcriptomes analyzed simultaneously thanks to two new techniques.

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image: How a Popular Probiotic Works

How a Popular Probiotic Works

By | April 16, 2015

Eating a type of bacterium encourages the activity of other gut microbes, according to a small study.

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