This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.

Chairman: Arnold Levine, chairman, department of molecular biology, Princeton University Barry Bloom, Weinstock Professor and Howard Hughes Medical Institute (HHMI) investigator, department of microbiology and immunology, Albert Einstein College of Medicine, New York Rebecca Buckley, professor of pediatrics and immunology, Duke University Medical Center Charles Carpenter, chairman, Office of AIDS Research Advisory Committee; professor of medicine,Brown University School of Medicine Don

Multiple candidates are in Phase 3 clinical trials for older adults and pregnant women, with some getting close to approval in the United States.

Viruses, Diseases Author: Karen Young Kreeger Sidebar: Professional Resources for Viral Disease Researchers In the mid- to late 1980s, numerous correlations were discovered between viruses and various types of cancers. For example, Epstein-Barr virus was associated with nasopharyngeal carcinoma and B-cell lymphoma, hepatitis B virus with liver cancer, and human papillomavirus with cervical cancer. Now, a decade later, basic and clinical scientists are finding out that viruses may also play a r

The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.

Author: SIMON SILVER Department of Microbiology & Immunology University of Illinois Chicago The Luddites have mostly won during the 15 years of recombinant DNA research and debates. An FDA report concludes that bovine growth hormone presents no increased health risk. Yet the combination of building political bases and mounting irrational fear of genetic engineering means that we will probably continue to be protected from this unreal danger. Our students have questioning minds, so this compilat

Ned Shaw US scientists have reason to feel both heady and scared. The federal government recently released unprecedented billions of dollars to fund bioterrorism research. Yet, the merits of this sudden shift in focus are being debated, and some worry that the money will be squandered or wasted. "I have been really very upset by the focus on bioterrorism," says Stanley Falkow, professor of microbiology and immunology and of medicine at Stanford University. "Everybody's talking about it, but th

Tools and tricks for high-throughput flow cytometry

Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.

Photo: Courtesy of NASA ON THE HORIZON: New technologies will protect the health of astronauts on long space flights. Researchers at the National Space Biomedical Research Institute (NSBRI) are developing technologies to identify and monitor anticipated and unanticipated microorganisms in space--technologies, they suggest, that could also help to more efficiently diagnose medical conditions down here on Earth, as well as help detect biological hazards in this post-Sept. 11 world.1-3 Geo