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image: Life Scientists Honored

Life Scientists Honored

By | November 9, 2015

Breakthrough Prizes of $3 million each go to five researchers in the life sciences, recognizing their pioneering work in optogenetics, disease-associated mutation analyses, and ancient DNA sequencing.

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image: Novel Hantavirus Infection Method

Novel Hantavirus Infection Method

By | July 3, 2015

Researchers find that the potentially deadly virus uses cholesterol to gain access to cells.


image: Enzyme Improves CRISPR

Enzyme Improves CRISPR

By | April 1, 2015

A smaller Cas9 protein enables in vivo genome engineering via viral vectors.


image: Crystal Structure, Murky Function

Crystal Structure, Murky Function

By | January 29, 2015

Scientists have determined the crystal structures of bacterial translocator proteins, but their functions remain unclear.


image: Mutation Tied to Reduced Heart Disease

Mutation Tied to Reduced Heart Disease

By | June 20, 2014

Genetic variants that cripple a triglyceride-producing protein are linked with a lower risk of heart attack and stroke.

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image: Path Finding

Path Finding

By | March 1, 2014

Biochemistry reveals the missing link in a pathway that archaea and some bacteria use to generate essential compounds.

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image: RNAi Remedy Lowers Cholesterol

RNAi Remedy Lowers Cholesterol

By | October 3, 2013

A Phase 1 clinical trial demonstrates the safety and efficacy of an siRNA-based, cholesterol-lowering drug.

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image: Obesity-Fighting Drug May Improve Metabolism

Obesity-Fighting Drug May Improve Metabolism

By | September 3, 2013

Initial tests of a hormone therapy suggest it reduces LDL cholesterol and improves weight loss in obese patients with type 2 diabetes.


image: Gene a Pain for Statin Users

Gene a Pain for Statin Users

By | August 28, 2013

A genetic variant may help explain why some patients experience muscle discomfort and dysfunction while taking the cholesterol-lowering medications.


image: Epigenetic Drug Improves Cholesterol Levels

Epigenetic Drug Improves Cholesterol Levels

By | August 28, 2012

Results from a Phase II trial for cardiovascular disease with an epigenetic target therapy show promise.

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