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tag induced pluripotent stem cell culture ecology neuroscience genetics genomics

Pluripotent Until Needed
Beth Marie Mole | Apr 1, 2013 | 7 min read
Microarrays help keep induced pluripotent stem cell lines in check, from start to finish.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Developing Brains in Dishes
Ashley P. Taylor | Apr 26, 2017 | 3 min read
Two studies report methods to mimic human fetal brain development using neurons derived from human induced pluripotent stem cells that form 3-D, brain-like structures. 
Harnessing Stem Cells to Model Neurological Disorders
The Scientist | Apr 15, 2021 | 2 min read
Gene-Edited Organoids Explore Neanderthal Brain Function
Jef Akst | Feb 12, 2021 | 3 min read
Using CRISPR to swap an archaic variant of the NOVA1 gene into human stem cells, researchers create organoids with neurodevelopmental differences from those carrying modern DNA.
Genetic Diversity in the Brain
Ruth Williams | Oct 31, 2013 | 3 min read
Neurons within a person’s brain exhibit striking variations in DNA copy number.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
A Paradigm Shift in Stem Cell Research?
Ricki Lewis | Mar 5, 2000 | 9 min read
Photo: E.D. Laywell, UT MemphisMultipotent clones of cells derived from the adult human brain With the promises and challenges of stem cell research in the headlines, visions of artificial livers dance in the public's eye. Bioethicists, politicians, and citizens alike continue to debate whether public funds should be used to obtain cells from human embryos and fetuses. On the scientific front, however, the implications of stem cell research are even more profound than offering replacement parts.
The Genes Underlying Autism Are Coming Into Focus
Megan Scudellari | Aug 1, 2016 | 10+ min read
As researchers sequence the DNA of thousands of kids with autism, dozens of genetic subgroups are emerging.
Into the Limelight
Kate Yandell | Oct 1, 2015 | 8 min read
Glial cells were once considered neurons’ supporting actors, but new methods and model organisms are revealing their true importance in brain function.

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