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tag induced pluripotent stem cell cell molecular biology developmental biology disease medicine

Biology’s New Supermodel
Megan Scudellari | Jul 20, 2011 | 5 min read
Induced pluripotent stem cells are biology’s hottest new tool for understanding human disease.
Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014 | 2 min read
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
Stem Cells Made Waves in Biology and Medicine
Karen Zusi | Oct 1, 2016 | 6 min read
Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.
Stem Cells Induced for Conservation
Kerry Grens | Sep 4, 2011 | 2 min read
Researchers generate pluripotent stem cells from two endangered species in hopes of learning more about the near-extinct animals.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Synthego Launches High Throughput Induced Pluripotent Stem Cell Genome Engineering
Synthego | Oct 29, 2019 | 2 min read
National Institutes of Health awards contract for CRISPR-based disease modeling in iPS cell lines associated with Alzheimer’s, Stem cell pioneer Bill Skarnes joins advisory board
Developmental Biology
The Scientist Staff | Feb 1, 1999 | 6 min read
Edited by: Paul Smaglik P. Carmeliet, V. Ferreira, G. Breier, S. Pollefeyt, L. Kieckens, M. Gertsenstein, M. Fahrig, A. Vandenhoeck, K. Harpal, C. Eberhardt, C. Declercq, J. Pawling, L. Moons, D. Collen, W. Risau, A. Nagy, "Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele," Nature, 380:435-9, 1996. (Cited in more than 235 papers since publication) Comments by Andras Nagy, senior staff scientist, Mount Sinai Hospital, Samuel Lunenfeld Research Institute, To
Using CRISPR to Edit Genes in Induced Pluripotent Stem Cells
Kelly Rae Chi | Sep 1, 2016 | 8 min read
Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.
Leveraging Stem Cells to Create Better Disease Models
Leveraging Stem Cells to Create Better Disease Models
The Scientist | May 29, 2023 | 2 min read
Clive Svendsen, Meritxell Huch, Ameen Salahudeen, and Maksim Plikus will discuss the latest advances in using patient-derived stem cells to create more accurate disease models.
Artist’s rendition of a blue-green DNA double helix, viewed lengthwise from within one end.
Stem Cell Lines Riddled With Undetected Mutations
Dan Robitzski | Aug 12, 2022 | 4 min read
Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.

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