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Hormonal sibling rivalry

By | December 5, 2005

Proteins that stimulate and repress appetite appear to be cut from the same cloth.

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Interdisciplinary Research

December 5, 2005

These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.N. Touret et al., "Quantitative and dynamic assessment of the contribution of the ER to phagosome formation," Cell, 123:157–170, Oct. 7, 2005.Aligning an impressive array of methods, this study provides strong evidence against the recently proposed model of a significant contribution of endoplasmic reticulum (ER) membranes during early phagosome

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Worms sniff out harm

By | December 5, 2005

Worms learn: If something makes you sick, don't eat it again.

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A flavor for fat?

By | November 21, 2005

Scientists have identified a candidate taste receptor for lipids.

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Clues to cell death in ALS

By | November 21, 2005

Neuronal cells clogged with a mutant protein associated with amyotrophic lateral sclerosis (ALS) die within hours after clumps first form, researchers report.1 The finding directly links aggregation of malformed proteins with cell death characteristic of the disease, the authors claim.By watching individual cells over the course of 48 hours, Richard Morimoto at Northwestern University and colleagues demonstrated that most cultured neurons die between 6 and 24 hours after mutant superoxide dismut

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Gene fusion identified in prostate cancer

By | November 21, 2005

Using a novel bioinformatics approach, researchers identified a gene fusion that seems to occur in a majority of prostate cancers.

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Cannabinoids boost neurogenesis?

By | November 7, 2005

Dope may help the growth of new brain cells.

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Getting on top, genetically

By | November 7, 2005

Take the bully out of the schoolyard and another quickly takes his place.

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Interdisciplinary Research

November 7, 2005

These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.A. O'Doherty et al., "An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes," Science, 309:2033–7, Sept. 23, 2005.This is the first study to show that a human chromosome can be introduced into a mouse's germline and transmitted to successive generations. The authors introduced a copy of human chromosome 21. The mice

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Blocking growth to regenerate nerves

By | October 24, 2005

Jamming the epidermal growth factor (EGF) receptor allows severed neurons to regenerate.1 "It's a surprising finding," says Martin Schwab of the University of Zurich, as activation of the EGF receptor is normally associated with proliferation and growth of cells.Previous research that sought to explain why mammalian axons fail to regenerate in the wounded brain or spinal cord found several inhibitory cues that prevent healing. The culprits include proteins associated with myelin and proteoglycan

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