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Proof for prions?

By | May 9, 2005

Protein aggregates generated in a test tube were found to infect wild-type hamsters with a disease much like scrapie.

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Wound repair in mouse and fly linked

By | May 9, 2005

The same family of transcription factors directs the epidermal wound repair in mice and flies, according to two research teams.

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Improving vaccines with adenovirus

By | April 25, 2005

Researchers at Cornell University's Weill Medical College in New York have created a successful vaccine strategy in mice that uses the immune system's typical antibody response to adenoviruses – which can prevent modified viruses from expressing their payloads and thus diminish the vaccine's efficacy – to boost the antibody response to the vaccine.1By attaching 720 copies of an immunogenic polypeptide from Pseudomonas aeruginosa to the capsid shell of a replication-deficient adenovir

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These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.S.J. Lolle et al., "Genome-wide non-mendelian inheritance of extra-genomic information in Arabidopsis," Nature, 434:505–9, March 24, 2005.This paper reports an unusual form of inheritance in Arabidopsis "hothead" mutants, where DNA sequence information absent in the parent but present in previous generations reappears at high frequency in selfed

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Quality control in the nucleus

By | April 25, 2005

Researchers have discovered the first protein quality control system in the yeast nucleus.

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hinders mismatch repair

By | April 11, 2005

National Cancer Institute researcher Eric Huang and colleagues have identified a mechanism that promotes mutations under hypoxic conditions.

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Mammals feed off yeast pathway

By | April 11, 2005

The biochemical pathway that senses amino acid deficiencies in yeast is also at work in mammals, according to researchers at the University of California, Davis.

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Sperm fusion protein identified

By | April 11, 2005

Japanese researchers have identified a sperm protein that is essential for the fusion of the sperm and egg membranes during fertilization.

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Evidence for organelle origin

By | March 28, 2005

according to Dutch and German researchers led by Johannes Hackstein of Radboud University Nijmegen in the Netherlands.

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Fast track to longevity

By | March 28, 2005

Researchers have moved a step forward in understanding how calorie restriction is linked to lifespan extension in mammals.

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