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New adipocytokine found

By | January 17, 2005

Adipose tissue does more than store triglycerides.

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Engineering attenuation

By | December 20, 2004

By exploiting a malaria parasite's "Achilles heel," researchers in Germany say a transgenic whole-organism vaccine for humans may be possible.

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Explaining the burst after urchin fertilization

By | December 20, 2004

Researchers have identified a key enzyme in sea urchin egg fertilization.

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Mice tolerate siRNAs

By | December 20, 2004

Small interfering RNAs (siRNAs) appear to silence genes in mice without triggering an immune response, according to researchers at the California Institute of Technology in Pasadena.

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Interdisciplinary Research

December 6, 2004

These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.T.A. Allen et al., "The SINE-encoded mouse B2 RNA represses mRNA transcription in response to heat shock," Nat Struct Mol Biol, 11:816–21, September 2004.A small, noncoding RNA, called B2, is expressed during heat shock and represses transcription from RNA polymerase II. Interestingly, B2 RNA is transcribed from a DNA region previously thought to

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Kicking the habit with RNAi

By | December 6, 2004

RNA interference can turn off morphine production in poppies, according to a group from the Commonwealth Scientific and Industrial Research Organization (CSIRO) Plant Industry in Canberra, Australia.

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Triassic reptiles had live young

By | December 6, 2004

The largest and most diverse group of Triassic aquatic reptiles gave birth to live young, researchers recently reported.

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Interdisciplinary Research

November 22, 2004

Courtesy of Mike SextonThese papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.L. Li et al., "A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death," Science, 305:1471–4, Sept. 3, 2004.This is the first study in which a true Smac mimetic was synthesized to antagonize the inhibitor-of-apoptosis (IAP) proteins. … Importantly, these compounds synergize with TNFα and

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Making Fish Genes Work in Human Cells

By | November 22, 2004

Findings on Fugu gene splicing could help scientists develop pufferfish transgenes for mammalian cells, say researchers at Massachusetts Institute of Technology.

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Wax on, the Mammalian Way

By | November 22, 2004

Plants export wax from epidermal cells to their external surfaces through a lipid transporter similar to those present in mammalian cells, according to a study from the University of British Columbia.

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