Adipose tissue does more than store triglycerides.
By exploiting a malaria parasite's "Achilles heel," researchers in Germany say a transgenic whole-organism vaccine for humans may be possible.
Researchers have identified a key enzyme in sea urchin egg fertilization.
Small interfering RNAs (siRNAs) appear to silence genes in mice without triggering an immune response, according to researchers at the California Institute of Technology in Pasadena.
These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.T.A. Allen et al., "The SINE-encoded mouse B2 RNA represses mRNA transcription in response to heat shock," Nat Struct Mol Biol, 11:816–21, September 2004.A small, noncoding RNA, called B2, is expressed during heat shock and represses transcription from RNA polymerase II. Interestingly, B2 RNA is transcribed from a DNA region previously thought to
RNA interference can turn off morphine production in poppies, according to a group from the Commonwealth Scientific and Industrial Research Organization (CSIRO) Plant Industry in Canberra, Australia.
The largest and most diverse group of Triassic aquatic reptiles gave birth to live young, researchers recently reported.
Courtesy of Mike SextonThese papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.L. Li et al., "A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death," Science, 305:1471–4, Sept. 3, 2004.This is the first study in which a true Smac mimetic was synthesized to antagonize the inhibitor-of-apoptosis (IAP) proteins. … Importantly, these compounds synergize with TNFα and
Findings on Fugu gene splicing could help scientists develop pufferfish transgenes for mammalian cells, say researchers at Massachusetts Institute of Technology.
Plants export wax from epidermal cells to their external surfaces through a lipid transporter similar to those present in mammalian cells, according to a study from the University of British Columbia.