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Focus on phosphorylation

By | January 1, 2009

Credit: Generated using Polyview-3D / A. Porollo, J. Meller (2007) Versatile Annotation and Publication Quality Visualization of Protein Complexes Using POLYVIEW-3D" /> Credit: Generated using Polyview-3D / A. Porollo, J. Meller (2007) Versatile Annotation and Publication Quality Visualization of Protein Complexes Using POLYVIEW-3D The paper: J. Villén et al., "Large-scale p

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Fungus, decoded

By | January 1, 2009

Credit: Courtesy of Fungal Biodiversity Center, Utrecht, the Netherlands" /> Credit: Courtesy of Fungal Biodiversity Center, Utrecht, the Netherlands The paper: H.J. Pel et al., "Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88," Nat Biotechnol, 25:221-31, 2007. (Cited in 65 papers) The gist: Hein Stam and colleagues at DSM Food Sciences in The Neth

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LPA leaps

By | December 1, 2008

Credit: Journal of Biological Chemistry, vol. 280, issue 41, 10/14/05, courtesy of Yuko Fujiwara, University of Tennessee Cancer Institute, Memphis, TN" /> Credit: Journal of Biological Chemistry, vol. 280, issue 41, 10/14/05, courtesy of Yuko Fujiwara, University of Tennessee Cancer Institute, Memphis, TN The paper: J. Chun et al., "GPR92 as a new G(12/13)- and G(q)-coupled lysophosphatidic acid receptor tha

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Mini Eukaryote

By | December 1, 2008

Credit: Wenche Eikrem and Jahn Throndsen / University of Oslo" /> Credit: Wenche Eikrem and Jahn Throndsen / University of Oslo The paper: E. Derelle et. al., "Genome analysis of the smallest free-living eukaryote Ostreococcus tauri unveils many unique features," Proc Natl Acad Sci, 103:11647-52, 2006. (Cited in 74 papers) The study: French, Belgian, and US scientists

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Use the force

By | December 1, 2008

Credit: Opabinia regalis / wikimedia.org" /> Credit: Opabinia regalis / wikimedia.org The paper: V. Hornak, et al., "Comparison of multiple Amber force fields and development of improved protein backbone parameters," Proteins Struc Funct Bioinfo, 65:712-25, 2006. (Cited in 58 papers) The gist: To improve a 25-year-old set of equations, called the Amber force field,

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Abundant archaea

By | November 1, 2008

Credit: COURTESY OF Jennifer M. Warner / Department of Biology, University of North Carolina-Charlotte" /> Credit: COURTESY OF Jennifer M. Warner / Department of Biology, University of North Carolina-Charlotte The paper: S. Leininger et al., "Archaea predominate among ammonia-oxidizing prokaryotes in soils," Nature, 442:806-9, 2006 (Cited in 84 papers) The surprise:

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Reserve power

By | November 1, 2008

Credit: Frank Vincentz / wikimedia.org" /> Credit: Frank Vincentz / wikimedia.org The paper: M. Lagouge et al., "Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α," Cell, 127:1109-22, 2006. (Cited in 139 papers) The finding: In 2006, Johan Auwerx of the Institute of Genetics and Molecular and Cellular Biology in France and colleagues trea

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Tree timer

By | November 1, 2008

Credit: © Pekka Parviainen / Photo Researchers, Inc." /> Credit: © Pekka Parviainen / Photo Researchers, Inc. The paper: Ove Nilsson et al. "CO/FT regulatory module controls timing of flowering and seasonal growth cessation in trees," Science, 312:1040-3, 2006. (Cited in 58 papers). The finding: While trying to speed up breeding in flowering trees, Ove Nilsson's group

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Effector detector

By | October 1, 2008

Credit: ® CAMR/A. Barry Dowsett / Photo Researchers, Inc." /> Credit: ® CAMR/A. Barry Dowsett / Photo Researchers, Inc. The paper: T. Tobe et al., "An extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their dissemination," Proc Nat Acad Sci, 103:14941-6, 2006. (Cited in 38 papers.) The study: Some virulent bacteria infec

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Elastic enzyme

By | October 1, 2008

Credit: Proc Natl Acad Sci, 103:13682-7, 2006 / ® 2006 National Academy of Sciences, U.S.A" /> Credit: Proc Natl Acad Sci, 103:13682-7, 2006 / ® 2006 National Academy of Sciences, U.S.A The paper: M. Ekroos and T. Sjögren, "Structural basis for ligand promiscuity in cytochrome P450 3A4," Proc Natl Acad Sci, 103:13682-7, 2006. (Cited in 78 papers)

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