Advertisement
The Scientist
The Scientist

Vision

Most Recent

Does Your Dog Understand You?

By | December 20, 2004

magazine, 71% of American men believe their dogs understand them at some telepathic level.

0 Comments

Conversations in Genetics

By | December 6, 2004

As formal and methodological as it sometimes appears, science remains at its heart a process of storytelling.

0 Comments

Navigating Nanotechnology Patent Thickets

By | December 6, 2004

The entire patent system is a delicate balancing act.

0 Comments

Cells for Building

By | November 22, 2004

Tissue engineering has taken on a new meaning in recent years, bringing the stuff of science fiction to the operating table.

0 Comments

The Future Looks Bright for Genetic Medicine

By | November 22, 2004

Today, gene therapy, genomics, and stem cell therapy are considered to be discrete fields of research.

0 Comments

A Battle Cry to Decipher Immunity

By | November 8, 2004

Courtesy of Luke A. O'NeillLuke A. O'NeillThe march to demystify mammalian immunity has been long and arduous. At the frontlines we face a dizzying array of biochemicals and interactions between multiple cell types aimed at detecting, eliminating, and remembering intruders. The regulation of this system often appears impenetrable.But recent advances in our understanding of innate immunity – that hard-wired, first line of defense that doesn't appear to adapt during infection – have se

0 Comments

How to Launch a Biotech Success

By | November 8, 2004

Christoph H. WestphalCourtesy of David Shopper PhotographyMost people say this is an industry driven by how much money a drug, such as Lipitor, can bring in. I would argue that Lipitor is a great molecule, but it's the people who made the molecule the number-one selling drug on the planet. It took a talented team of chemists, clinicians, marketing executives, and regulatory experts to drive it to $4 billion in sales. The original discovery of a target is a small part of the value chain; you need

0 Comments

Cutting Drug Discovery Costs on the Subcontinent

By | October 25, 2004

Costs fo Drugs: Discovery-ApprovalDiscovery• Target identification• Target validation• Lead identification• Lead validationPre-Clinical Studies• In vitro validation• In vivo validationPre-Clinical Studies• In vitro validation• In vivo validationClinical Trials• Phase I trials• Phase II trials• Phase III trials• Regulatory affairsPercentages represent the total cost associated with that activityThe process of discovering new

0 Comments

For Olfaction, a Hypothesis is Felled

By | October 25, 2004

Peter MombaertsCourtesy of Peter MombaertsRarely do scientific studies claim that something is not the case. Rarer still do negative results appear in top-tier journals. Yet two recent papers in Nature describe what olfactory sensory neurons do not do.12The olfactory system is often compared to the immune system. The key cell types in each system, the olfactory sensory neuron (OSN) and the lymphocyte, can detect a wide variety of chemicals, both natural and synthetic. Chemical recognition by the

0 Comments

Charting the Microarray Revolution

By | October 11, 2004

In the early 1990s, my colleagues and I at Stanford University began tinkering with an interesting weed, the small flowering mustard plant, Arabidopsis thaliana. We set out to study genes involved in controlling the growth and appearance of this lauded model organism, and using molecular cloning and transgenics, we identified a novel family of plant homeobox genes.This experiment proved valuable in a number of respects. First, we showed we could hasten or slow the rate of plant development by al

0 Comments

Advertisement
NeuroScientistNews
NeuroScientistNews

Follow The Scientist

icon-facebook icon-linkedin icon-twitter icon-vimeo icon-youtube
Advertisement
The Scientist
The Scientist

Stay Connected with The Scientist

  • icon-facebook The Scientist Magazine
  • icon-facebook The Scientist Careers
  • icon-facebook Neuroscience Research Techniques
  • icon-facebook Genetic Research Techniques
  • icon-facebook Cell Culture Techniques
  • icon-facebook Microbiology and Immunology
  • icon-facebook Cancer Research and Technology
  • icon-facebook Stem Cell and Regenerative Science
Advertisement
The Scientist
The Scientist
Advertisement
NeuroScientistNews
NeuroScientistNews
Life Technologies