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tag stem cell trials microbiology genetics genomics stem cells

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Genotoxic Effects of Base and Prime Editing
Kamal Nahas, PhD | Jan 12, 2024 | 5 min read
A risk-benefit analysis of gene editing tools in stem cells revealed that base and prime editing carry vulnerabilities similar to those of CRISPR-Cas9, but at a reduced rate. 
Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014 | 2 min read
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
A Master Regulator of Gene Expression
Mariella Bodemeier Loayza Careaga, PhD | Jan 31, 2024 | 4 min read
A CRISPR-based screening platform helped scientists identify a transcription factor that makes CAR T cells better at killing cancer cells. 
Long-Lived Immunotherapy Stem Cells
Ruth Williams | Feb 4, 2015 | 3 min read
Genetically modified T memory stem cells persist in patients for more than 10 years, and can differentiate into a variety of T cell types.
Stem Cells: Safe Haven For TB
Nsikan Akpan | Feb 5, 2013 | 3 min read
Tuberculosis bacteria find shelter from drugs and the body’s defenses in bone marrow stem cells.
Julie Trolle and Jef Boeke
Self Sufficient Cells?
Katherine Irving | Jun 1, 2023 | 4 min read
Animal cells cannot produce 9 of the 20 amino acids they need to function. Some researchers are looking to change that.
Patched-up human stem cells
Elie Dolgin | May 30, 2009 | 3 min read
For the first time, researchers have combined gene therapy and cellular reprogramming technologies in human cells to correct a genetic defect. After taking skin and hair cells from patients with a rare genetic disorder and fixing the aberrant mutation, the investigators successfully reprogrammed the cells to an embryonic-like state and then turned them into the very cell types that usually go awry, according to a linkurl:study;http://www.nature.com/nature/journal/vaop/ncurrent/abs/nature08129.ht
Not All Stem Cells Created Equal
Anna Azvolinsky | Jul 2, 2014 | 4 min read
Compared to induced pluripotent stem cells generated from somatic cells, stem cells created by nuclear transfer appear to be closer to the genetic state of embryonic cells.
Synthego Launches High Throughput Induced Pluripotent Stem Cell Genome Engineering
Synthego | Oct 29, 2019 | 2 min read
National Institutes of Health awards contract for CRISPR-based disease modeling in iPS cell lines associated with Alzheimer’s, Stem cell pioneer Bill Skarnes joins advisory board

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